Thrombin inhibitor 1

Modify Date: 2025-09-05 22:05:22

Thrombin inhibitor 1 structure	Common Name	Thrombin inhibitor 1
	CAS Number	855998-46-8	Molecular Weight	497.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₀Cl₂F₂N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thrombin inhibitor 1

Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).

Name	Thrombin inhibitor 1

Description	Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin Research Areas >> Cardiovascular Disease
Target	Ki: 0.66 nM (thrombin)[1]
In Vitro	Thrombin inhibitor 1 (Compound 4) is binds in the active site of thrombin with Ki of 0.66 nM, 2xaPTT=0.43 uM). Thrombin inhibitor 1 (Compound 4) is evaluated for its thrombin inhibitory potency and its functional ability to double the activated partial thromboplastin time (2xaPTT) in human plasma with a 2xaPTT of 0.43 μM[1].
References	[1]. Nantermet PG, et al. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5.

Molecular Formula	C₂₂H₂₀Cl₂F₂N₄O₃
Molecular Weight	497.32

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Product Name: Thrombin inhibitor 1
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