DSS30
Modify Date: 2025-11-28 18:01:33
DSS30 structure
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Common Name | DSS30 | ||
|---|---|---|---|---|
| CAS Number | 883027-32-5 | Molecular Weight | 367.87 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14ClNO3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DSS30DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease[1]. |
| Name | DSS30 |
|---|
| Description | DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease[1]. |
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| Related Catalog | |
| In Vitro | DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1]. Western Blot Analysis[1] Cell Line: Expressed P25 PC12tet-off cell lines Concentration: 50 μM Incubation Time: 8 hours Result: Inhibited BACE1 phosphorylation by 12%. |
| References |
| Molecular Formula | C16H14ClNO3S2 |
|---|---|
| Molecular Weight | 367.87 |
| InChIKey | RPELAWNEKQODNO-UHFFFAOYSA-N |
| SMILES | COc1ccccc1NS(=O)(=O)c1sc2ccc(Cl)cc2c1C |