Cilazapril
Modify Date: 2024-01-02 18:23:07
Cilazapril structure
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Common Name | Cilazapril | ||
|---|---|---|---|---|
| CAS Number | 88768-40-5 | Molecular Weight | 417.49900 | |
| Density | 1.26g/cm3 | Boiling Point | 598.1ºC at 760 mmHg | |
| Molecular Formula | C22H31N3O5 | Melting Point | 95-97ºC | |
| MSDS | N/A | Flash Point | 315.5ºC | |
Use of CilazaprilCilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.Target: ACECilazapril is a new nonthiol group containing angiotensin converting enzyme (ACE) inhibitor. Cilazapril has been investigated in more than 4000 patients with all degrees of hypertension, as well as in the special patient groups such as the elderly, renally impaired, and patients with concomitant diseases, such as congestive cardiac failure or chronic obstructive pulmonary disease [1]. Cilazapril is a very potent and highly effective converting enzyme inhibitor. Doses well below 5 mg/day will probably suffice for therapeutic efficacy [2]. |
| Name | (4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid |
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| Synonym | More Synonyms |
| Description | Cilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.Target: ACECilazapril is a new nonthiol group containing angiotensin converting enzyme (ACE) inhibitor. Cilazapril has been investigated in more than 4000 patients with all degrees of hypertension, as well as in the special patient groups such as the elderly, renally impaired, and patients with concomitant diseases, such as congestive cardiac failure or chronic obstructive pulmonary disease [1]. Cilazapril is a very potent and highly effective converting enzyme inhibitor. Doses well below 5 mg/day will probably suffice for therapeutic efficacy [2]. |
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| Related Catalog | |
| References |
[1]. Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24. |
| Density | 1.26g/cm3 |
|---|---|
| Boiling Point | 598.1ºC at 760 mmHg |
| Melting Point | 95-97ºC |
| Molecular Formula | C22H31N3O5 |
| Molecular Weight | 417.49900 |
| Flash Point | 315.5ºC |
| Exact Mass | 417.22600 |
| PSA | 99.18000 |
| LogP | 1.86220 |
| Vapour Pressure | 3.73E-15mmHg at 25°C |
| Index of Refraction | 1.591 |
| Storage condition | 2-8°C |
| Safety Phrases | 22-24/25 |
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| RTECS | MJ9650200 |
| Precursor 7 | |
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| DownStream 2 | |
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CAS#:88784-33-2![tert-butyl (4S,7R)-7-(1,3-dioxoisoindol-2-yl)-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylate Structure](https://www.chemsrc.com/caspic/002/106927-97-3.png)
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CAS#:90139-06-3
CAS#:64-17-5| Ro 34-2848 |
| (1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid |
| 9(S)-[1-(S)-(ethoxycarbony)-3-phenylpropylamino]octahydro-10-oxo-6H-pyridazo[1,2-a][1,2]-diazepine-1(S)-carboxylic acid |
| (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid |
| Cilazaprilum [Latin] |
| Cilazaprilum |
| MFCD08459332 |
| Cilazil |
| EINECS 279-694-4 |
| Cilazapril |