3,5-DIHYDROXY-2-NAPHTHOIC ACID

Modify Date: 2025-08-20 19:27:42

3,5-DIHYDROXY-2-NAPHTHOIC ACID Structure
3,5-DIHYDROXY-2-NAPHTHOIC ACID structure
Common Name 3,5-DIHYDROXY-2-NAPHTHOIC ACID
CAS Number 89-35-0 Molecular Weight 204.18
Density 1.5±0.1 g/cm3 Boiling Point 442.2±35.0 °C at 760 mmHg
Molecular Formula C11H8O4 Melting Point 275-280 °C(lit.)
MSDS Chinese USA Flash Point 235.3±22.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 3,5-DIHYDROXY-2-NAPHTHOIC ACID


3,5-Dihydroxy-2-naphthoic acid is a Naphthoic acid derivative. Naphthoic acid is a NMDA receptor allosteric modulator[1].

 Names

Name 3,5-Dihydroxy-2-naphthoic acid
Synonym More Synonyms

 3,5-DIHYDROXY-2-NAPHTHOIC ACID Biological Activity

Description 3,5-Dihydroxy-2-naphthoic acid is a Naphthoic acid derivative. Naphthoic acid is a NMDA receptor allosteric modulator[1].
Related Catalog
References

[1]. Monaghan DT, et al. Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators. Neurochem Int. 2012 Sep;61(4):581-92.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 442.2±35.0 °C at 760 mmHg
Melting Point 275-280 °C(lit.)
Molecular Formula C11H8O4
Molecular Weight 204.18
Flash Point 235.3±22.4 °C
Exact Mass 204.042252
PSA 77.76000
LogP 2.52
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.762
InChIKey YELLAPKUWRTITI-UHFFFAOYSA-N
SMILES O=C(O)c1cc2cccc(O)c2cc1O

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918290000

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Articles1

More Articles
Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

J. Biol. Chem. 283(21) , 14694-702, (2008)

Neocarzinostatin, a clinical anticancer drug, is the archetypal member of the chromoprotein family of enediyne antitumor antibiotics that are composed of a nonprotein chromophore and an apoprotein. Th...

 3,5-DIHYDROXY-2-NAPHTHOIC ACIDBioassay

View more

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenop...
Source: ChEMBL
Target: Glutamate receptor ionotropic, NMDA 2D
External Id: CHEMBL4309008
Name: Inhibition of Mycobacterium tuberculosis IMPDH deltaCBS mutant assessed as reduction ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4222538
Name: Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenop...
Source: ChEMBL
Target: Glutamate receptor ionotropic, NMDA 2C
External Id: CHEMBL4309006
Name: Negative allosteric modulation of GluN2B receptor (unknown origin) expressed in xenop...
Source: ChEMBL
Target: Glutamate receptor ionotropic, NMDA 2B
External Id: CHEMBL4309004
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Negative allosteric modulation of GluN2A receptor (unknown origin) expressed in xenop...
Source: ChEMBL
Target: Glutamate receptor ionotropic, NMDA 2A
External Id: CHEMBL4309003
Total 8, Current Page 1 of 1
1

 Synonyms

3,5-DIHYDROXY-2-NAPHTHOIC ACID
3,5-dihydroxynaphthalene-2-carboxylic acid
EINECS 201-900-8
MFCD00003982
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.