BR1
Modify Date: 2025-08-22 21:41:47
BR1 structure
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Common Name | BR1 | ||
|---|---|---|---|---|
| CAS Number | 893449-38-2 | Molecular Weight | 485.21300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H11Br2NO2S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of BR1PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay[1]. |
| Name | 4-Thiazolidinone, 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo |
|---|---|
| Synonym | More Synonyms |
| Description | PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.9 μM (PRL-3)[1] |
| In Vitro | PRL-3 Inhibitor I reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay[1]. |
| References |
| Molecular Formula | C17H11Br2NO2S2 |
|---|---|
| Molecular Weight | 485.21300 |
| Exact Mass | 482.86000 |
| PSA | 95.72000 |
| LogP | 5.60820 |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H410 |
| Precautionary Statements | P261-P273-P305 + P351 + P338-P501 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | UN 3077 9 / PGIII |
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Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors.
Bioorg. Med. Chem. Lett. 16 , 2996-2999, (2006) A series of rhodanine derivatives was synthesized and evaluated for their ability to inhibit PRL-3. Benzylidene rhodanine derivative showed good biological activity, while compound 5e was the most act... |
| prl-3 inhibitor i |
| prl-3 inhibitor |