Prunetin 5-O-β-D-glucopyranoside

Modify Date: 2024-01-08 22:47:28

Prunetin 5-O-β-D-glucopyranoside Structure
Prunetin 5-O-β-D-glucopyranoside structure
Common Name Prunetin 5-O-β-D-glucopyranoside
CAS Number 89595-66-4 Molecular Weight 446.40400
Density 1.545g/cm3 Boiling Point 771ºC at 760 mmHg
Molecular Formula C22H22O10 Melting Point N/A
MSDS N/A Flash Point 271.3ºC

 Use of Prunetin 5-O-β-D-glucopyranoside


Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes[1].

 Names

Name 5,4'-dihydroxy-7-methoxyisoflavone-4'-o-glucoside
Synonym More Synonyms

 Prunetin 5-O-β-D-glucopyranoside Biological Activity

Description Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes[1].
Related Catalog
Target

IC50: 56.05 μg/mL (α-glucosidase)[1]

References

[1]. Şöhretoğlu D, et, al. α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1062-1070.

 Chemical & Physical Properties

Density 1.545g/cm3
Boiling Point 771ºC at 760 mmHg
Molecular Formula C22H22O10
Molecular Weight 446.40400
Flash Point 271.3ºC
Exact Mass 446.12100
PSA 159.05000
LogP 0.35290
Index of Refraction 1.674

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

prunetin-4'-glucoside
prunitrin