Glucose oxidase

Modify Date: 2024-01-02 23:52:36

Glucose oxidase Structure
Glucose oxidase structure
Common Name Glucose oxidase
CAS Number 9001-37-0 Molecular Weight 154.120
Density 1.5±0.1 g/cm3 Boiling Point 513.7±50.0 °C at 760 mmHg
Molecular Formula C6H12O6 Melting Point N/A
MSDS Chinese USA Flash Point 226.8±23.6 °C
Symbol GHS08
GHS08
Signal Word Danger

 Use of Glucose oxidase


Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation[1][2][3].

 Names

Name Oxidase glucose
Synonym More Synonyms

 Glucose oxidase Biological Activity

Description Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation[1][2][3].
Related Catalog
Target

Microbial Metabolite

In Vitro Glucose oxidase is a subset of oxidoreductase enzymes that catalyzes the transfer of electrons from an oxidant to a reductant. Glucose oxidases use oxygen as an external electron acceptor that releases hydrogen peroxide (H2 O2). Glucose oxidase has many applications in commercial processes, including improving the color and taste, increasing the persistence of food materials, removing the glucose from the dried egg, and eliminating the oxygen from different juices and beverages[4].
References

[1]. Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66(3):300]. Regul Toxicol Pharmacol. 2013;66(1):13-23.

[2]. Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37(4):731-750.

[3]. Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15(51):e1903895.

[4]. Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 513.7±50.0 °C at 760 mmHg
Molecular Formula C6H12O6
Molecular Weight 154.120
Flash Point 226.8±23.6 °C
Exact Mass 154.026611
LogP -0.75
Appearance of Characters solution (clear) | yellow
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.603
Storage condition 2-8°C

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H334
Precautionary Statements P261-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn,Xi
Risk Phrases 42-36/37/38
Safety Phrases 45-22-23-36-26-24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS RQ8452000
HS Code 35079090

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 Synonyms

beta-D-Glucose:quinone oxidoreductase
(2,4-Dihydroxy-2H-pyran-3(6H)-ylidene)acetic Acid 3,4-Lactone
Alfamalt Gloxyl 4080
4H-Furo(3,2-c)pyran-2(6H)-one, 4-hydroxy-
DL-Patulin
Mycoin C3
beta-D-Glucose oxidase
Clavacin
Claviformin
EINECS 232-601-0
Penicidin
Clairformin
Patulin
Bakezyme G01500
gigantin
MFCD00131182
Clavatin
Patuline
Claviform
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
4H-Furo[3,2-c]pyran-2(6H)-one, 4-hydroxy-
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