plasmin

Modify Date: 2024-01-11 00:10:22

plasmin Structure
plasmin structure
Common Name plasmin
CAS Number 9001-90-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C28H38N6O9S Melting Point N/A
MSDS USA Flash Point N/A

 Use of plasmin


Plasmin is an important protease present in blood that degrades many plasma proteins, including fibrin clots. Plasmin can also act as a potent regulator of the immune process and can directly interact with various cell types, including monocytes, macrophages, and dendritic cells[1][2].

 Names

Name N-[(4-Methylphenyl)sulfonyl]glycylprolyl-N-(4-nitrophenyl)lysinamide acetate (1:1)
Synonym More Synonyms

 plasmin Biological Activity

Description Plasmin is an important protease present in blood that degrades many plasma proteins, including fibrin clots. Plasmin can also act as a potent regulator of the immune process and can directly interact with various cell types, including monocytes, macrophages, and dendritic cells[1][2].
Related Catalog
In Vitro Plasmin (20 μg/mL, 24 h) 在小鼠皮质管上皮细胞系 (MCT) 中可以激活 PAR-1,强烈诱导 ERK 磷酸化,降解 e -钙粘蛋白[1]。
References

[1]. Guoqiang Zhang, et al. Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals. J Am Soc Nephrol. 2007 Mar;18(3):846-59.   

[2]. Dominik F Draxler, et al. Plasmin: A Modulator of Immune Function. Semin Thromb Hemost. 2017 Mar;43(2):143-153.   

 Chemical & Physical Properties

Molecular Formula C28H38N6O9S
Appearance of Characters lyophilized powder
Storage condition −20°C

 Safety Information

Hazard Codes B,Xn
Risk Phrases 36/37/38-42
Safety Phrases 2-22-24-26-36/37-45-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles59

More Articles
Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin is independent of the viral neuraminidase.

J. Virol. 87(9) , 5161-9, (2013)

Influenza virus is well recognized to modulate host tropism and pathogenesis based on mutations in the proteolytic cleavage site of the viral hemagglutinin (HA), which activates HA and exposes the fus...

Effects of black cohosh on the plasminogen activator system in vascular smooth muscle cells.

Maturitas 76(1) , 75-80, (2013)

The rhizome of the Cimicifuga racemosa plant (commonly known as black cohosh) has been used for menopausal complaints. Studies regarding the cardiovascular effects of black cohosh are lacking. We inve...

Functional characterization of a slow and tight-binding inhibitor of plasmin isolated from Russell's viper venom.

Biochim. Biophys. Acta 1840(1) , 153-9, (2014)

Snake venoms are rich in Kunitz-type protease inhibitors that may have therapeutic applications. However, apart from trypsin or chymotrypsin inhibition, the functions of most of these inhibitors have ...

 Synonyms

MFCD00131921
Lysinamide, N-[(4-methylphenyl)sulfonyl]glycylprolyl-N-(4-nitrophenyl)-, acetate (1:1)
N-[(4-Methylphenyl)sulfonyl]glycylprolyl-N-(4-nitrophenyl)lysinamide acetate (1:1)
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