Phosphorylase purine nucleoside

Modify Date: 2024-01-05 12:36:02

Phosphorylase purine nucleoside Structure
Phosphorylase purine nucleoside structure
Common Name Phosphorylase purine nucleoside
CAS Number 9030-21-1 Molecular Weight 143.574
Density 1.4±0.1 g/cm3 Boiling Point 409.3±40.0 °C at 760 mmHg
Molecular Formula C5H6ClN3 Melting Point N/A
MSDS USA Flash Point 201.3±27.3 °C

 Use of Phosphorylase purine nucleoside


Purine nucleoside phosphorylase is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].

 Names

Name 6-chloropyridine-3,4-diamine
Synonym More Synonyms

 Phosphorylase purine nucleoside Biological Activity

Description Purine nucleoside phosphorylase is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].
Related Catalog
References

[1]. Bzowska A, et al. Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacol Ther. 2000 Dec;88(3):349-425.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 409.3±40.0 °C at 760 mmHg
Molecular Formula C5H6ClN3
Molecular Weight 143.574
Flash Point 201.3±27.3 °C
Exact Mass 143.025024
PSA 64.93000
LogP 1.09
Appearance of Characters lyophilized powder
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.685
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes B
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles94

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Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet. 36 , 40-5, (2004)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for...

 Synonyms

2-Chloro-4,5-diaminopyridine
3,4-Pyridinediamine, 6-chloro-
6-Chloro-3,4-diaminepyridine
6-chloropyridine-3,4-diamine
6-Chloro-3,4-diaminopyridine
3,4-Pyridinediamine,6-chloro
6-Chloro-3,4-pyridinediamine