m-PEG10-CH2COOH

Modify Date: 2024-01-03 04:34:04

m-PEG10-CH2COOH Structure
m-PEG10-CH2COOH structure
Common Name m-PEG10-CH2COOH
CAS Number 908258-58-2 Molecular Weight 530.60400
Density 1.122 Boiling Point N/A
Molecular Formula C23H46O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG10-CH2COOH


m-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 m-PEG10-CH2COOH Biological Activity

Description m-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.122
Molecular Formula C23H46O13
Molecular Weight 530.60400
Exact Mass 530.29400
PSA 138.83000

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]-ethoxy}ethoxy)acetic acid
3,6,9,12,15,18,21,24,27,30,33-UNDECAOXATETRATRIACONTANOIC ACID