OPIPRAMOL DIHYDROCHLORIDE

Modify Date: 2024-01-12 08:23:18

OPIPRAMOL DIHYDROCHLORIDE Structure
OPIPRAMOL DIHYDROCHLORIDE structure
 Common Name OPIPRAMOL DIHYDROCHLORIDE
CAS Number 909-39-7 Molecular Weight 436.41800
Density N/A Boiling Point N/A
Molecular Formula C23H31Cl2N3O Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS09
GHS07, GHS09		 Signal Word Warning

 Names

Name 2-[4-(3-benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol,dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C23H31Cl2N3O
Molecular Weight 436.41800
Exact Mass 435.18400
PSA 29.95000
LogP 4.85330

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL9100000
CHEMICAL NAME :
1-Piperazineethanol, 4-(3-(5H-dibenz(b,f)azepin-5-yl)propyl)-, dihydrochloride
CAS REGISTRY NUMBER :
909-39-7
LAST UPDATED :
199606
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C23-H29-N3-O.2Cl-H
MOLECULAR WEIGHT :
436.47
WISWESSER LINE NOTATION :
T C676 BNJ B3- AT6N DNTJ D2Q &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
36 mg/kg/25D-C
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
AJPSAO American Journal of Psychiatry. (American Psychiatric Assoc., Circulation Dept., 1400 K St., NW, Washington, DC 20005) V.78- 1921- Volume(issue)/page/year: 119,465,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,161,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
497 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
443 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RSPSA2 Rassegna di Studi Psichiatrici. Review of Psychiatric Studies. (Ospedale Psichiatrico, 53100 Siena, Italy) V.1- 1911- Volume(issue)/page/year: 52,204,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
315 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
45 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
11 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 148,560,1964

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H410
Precautionary Statements P273-P501
Risk Phrases 22-50/53
Safety Phrases 60-61
RIDADR UN 3077 9 / PGIII
RTECS TL9100000

 Articles25

More Articles
Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression.

World J. Biol. Psychiatry 7(4) , 261-4, (2006)

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive experimental technique which has mostly been investigated in the treatment of mood disorders with possible efficacy in depression....
In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side effects of the drugs.

Chem. Res. Toxicol. 23(9) , 1497-503, (2010)

Studies show that tricyclic antidepressants prescribed for migraines, anxiety, and child enuresis have numerous adverse effects in living cells. One of the undesired outcomes observed under treatment ...
Opipramol improves subjective quality of sleep the night prior to surgery: confirmatory testing of a double-blind, randomized clinical trial.

Neuropsychobiology 64(1) , 24-31, (2011)

Due to its pharmacological properties, opipramol may be useful in the context of evening premedication in anaesthesiology. This trial examines whether quality of sleep the night prior to surgery can b...

 Synonyms

4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol,dihydrochloride
Pramolan
Opipramol-dihydrochlorid
Insidon
UNII-B49OBI656M
Opipramol dihydrochloride
Opipramol hydrochloride
EINECS 213-000-2
Opipramol hydrochloride [USAN]
Ensidon
Opipramol HCl
Top Suppliers:I want be here

Get all suppliers and price by the below link:

OPIPRAMOL DIHYDROCHLORIDE suppliers

OPIPRAMOL DIHYDROCHLORIDE price

Related Compounds: More...
Gamma glutamyltransferase
9046-27-9
opipramol
315-72-0
Benzylhydrazine dihydrochloride
20570-96-1
Gosogliptin dihydrochloride
869490-47-1
Furosine dihydrochloride
157974-36-2
Inolitazone (dihydrochloride)
223132-38-5
5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol,hydrate,dihydrochloride
60479-98-3
Cyclobutylhydrazine dihydrochloride
1156980-49-2
OCTADECANEDIAMINE,DIHYDROCHLORIDE
63906-90-1
Chemsrc provides OPIPRAMOL DIHYDROCHLORIDE(CAS#:909-39-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of OPIPRAMOL DIHYDROCHLORIDE are included as well.>> amp version: OPIPRAMOL DIHYDROCHLORIDE

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved