TTA-Q6

Modify Date: 2024-01-10 11:26:25

TTA-Q6 Structure
TTA-Q6 structure
Common Name TTA-Q6
CAS Number 910484-28-5 Molecular Weight 405.80100
Density N/A Boiling Point N/A
Molecular Formula C20H15ClF3N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TTA-Q6


TTA-Q6 is a selective T-type Ca2+ channel antagonist, used in the neurological disease.

 Names

Name 4-[(4S)-6-Chloro-4-cyclopropyl-2-oxo-3-(2,2,2-trifluoroethyl)-1,2 ,3,4-tetrahydro-4-quinazolinyl]benzonitrile
Synonym More Synonyms

 TTA-Q6 Biological Activity

Description TTA-Q6 is a selective T-type Ca2+ channel antagonist, used in the neurological disease.
Related Catalog
Target

T-type Ca2+ channel[1]

In Vitro TTA-Q6 is a selective T-type Ca2+ channel antagonist, with 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay[1].
References

[1]. Schlegel KA, et al. Discovery and expanded SAR of 4,4-disubstituted quinazolin-2-ones as potent T-type calcium channel antagonists. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5147-52.

 Chemical & Physical Properties

Molecular Formula C20H15ClF3N3O
Molecular Weight 405.80100
Exact Mass 405.08600
PSA 59.62000
LogP 4.66218
Storage condition 2-8℃

 Synonyms

DETROL
tolterodine tartarate
TOLERODINETARTRATE
Detrol LA
TOLTERODINE L-TARTRATE
DETRUSITOL
Tolterodine Tartrate API
TTA-Q6
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