UDP-α-D-N-Acetylglucosamine Disodium Salt

Modify Date: 2024-01-03 21:19:00

UDP-α-D-N-Acetylglucosamine Disodium Salt Structure
UDP-α-D-N-Acetylglucosamine Disodium Salt structure
Common Name UDP-α-D-N-Acetylglucosamine Disodium Salt
CAS Number 91183-98-1 Molecular Weight 651.31700
Density N/A Boiling Point N/A
Molecular Formula C17H25N3Na2O17P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of UDP-α-D-N-Acetylglucosamine Disodium Salt


UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).

 Names

Name UDP-α-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
Synonym More Synonyms

  Biological Activity

Description UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).
Related Catalog
In Vitro OGT is a nucleocytoplasmic glycosyltransferase (uridine diphospho-N--acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase or O-GlcNAc transferase) assigned to the GT41 family in the CAZY (Carbohydrate-Active enZYme) database. Using UDP-GlcNAc Disodium Salt (UDP-GlcNAc) as the donor substrate, this enzyme modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within cytosol and nucleus[1].
References

[1]. Lefebvre T, et al. Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc. Methods Mol Biol. 2013;1022:147-59.

 Chemical & Physical Properties

Molecular Formula C17H25N3Na2O17P2
Molecular Weight 651.31700
Exact Mass 651.04500
PSA 331.14000
Storage condition −20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 22-26-36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29349990

 Articles21

More Articles
Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.

Drug Metab. Dispos. 43(1) , 147-53, (2014)

This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

Enhanced transfer of a photocross-linking N-acetylglucosamine (GlcNAc) analog by an O-GlcNAc transferase mutant with converted substrate specificity.

J. Biol. Chem. 290 , 22638-48, (2015)

O-Linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification of proteins in multicellular organisms. O-GlcNAc modification is catalyzed by the O-GlcNAc transferase (OGT), which trans...

A new antibiotic kills pathogens without detectable resistance.

Nature 517(7535) , 455-9, (2015)

Antibiotic resistance is spreading faster than the introduction of new compounds into clinical practice, causing a public health crisis. Most antibiotics were produced by screening soil microorganisms...

 Synonyms

URIDINE 5-DIPHOSPHO-N-ACETYLGLUCOSAMINE
MFCD00799985
UDPAG SODIUM SALT
UDP-GlcNAc disodium salt
EINECS 293-820-5
UDP-A-D-N-ACETYL-GLUCOSAMINE
UDPAG
UDP-GLCNAC,2NA
UDP-GLCNAC,NA2
UDP-N-ACETYLGLUCOSAMINE DISODIUM SALT
UDP-N-acetyl-D-glucosamine disodium salt
udp-glcnac
uridine 5'-diphosphate-N-acetylglucosamine disodium salt
UDP-α-D-N-Acetylglucosamine Disodium Salt