NS 9283

Modify Date: 2025-08-25 14:43:38

NS 9283 Structure
NS 9283 structure
Common Name NS 9283
CAS Number 913830-15-6 Molecular Weight 248.24000
Density 1.37±0.1 g/cm3(20 °C , 760mmHg) Boiling Point 469.9±55.0 °C (760 mmHg)
Molecular Formula C14H8N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NS 9283


NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease and Alzheimer's disease[1].

 Names

Name Benzonitrile, 3-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]-
Synonym More Synonyms

 NS 9283 Biological Activity

Description NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease and Alzheimer's disease[1].
Related Catalog
References

[1]. M Grupe, et al. Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2) 2nicotinic ACh receptors. Br J Pharmacol. 2013 Apr;168(8):2000-10.

 Chemical & Physical Properties

Density 1.37±0.1 g/cm3(20 °C , 760mmHg)
Boiling Point 469.9±55.0 °C (760 mmHg)
Molecular Formula C14H8N4O
Molecular Weight 248.24000
Exact Mass 248.07000
PSA 75.60000
LogP 2.67028

 Synonyms

3-[3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl]benzonitrile
NS 9283
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