2-(Triflouomethyl) phenothiazine

Modify Date: 2025-08-25 12:37:07

2-(Triflouomethyl) phenothiazine structure	Common Name	2-(Triflouomethyl) phenothiazine
	CAS Number	92-30-8	Molecular Weight	267.270
	Density	1.4±0.1 g/cm3	Boiling Point	361.1±42.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₈F₃NS	Melting Point	188-190 °C(lit.)
	MSDS	N/A	Flash Point	172.2±27.9 °C

Name	2-(Trifluoromethyl)phenothiazine
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	361.1±42.0 °C at 760 mmHg
Melting Point	188-190 °C(lit.)
Molecular Formula	C₁₃H₈F₃NS
Molecular Weight	267.270
Flash Point	172.2±27.9 °C
Exact Mass	267.032959
PSA	37.33000
LogP	5.50
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.588
InChIKey	RKGYJVASTMCSHZ-UHFFFAOYSA-N
SMILES	FC(F)(F)c1ccc2c(c1)Nc1ccccc1S2
Storage condition	2-8°C

2-(Triflouomethyl) phenothiazine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP5620000

CHEMICAL NAME :: Phenothiazine, 2-(trifluoromethyl)-

CAS REGISTRY NUMBER :: 92-30-8

BEILSTEIN REFERENCE NO. :: 0226580

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H8-F3-N-S

MOLECULAR WEIGHT :: 267.28

WISWESSER LINE NOTATION :: T C666 BM ISJ EXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 520 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - rigidity (including catalepsy) Behavioral - muscle contraction or spasticity

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,110,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07426

Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S36
WGK Germany	3
RTECS	SP5620000
HS Code	2934300000

Precursor 7
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HS Code	2934300000
Summary	2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Source: ChEMBL
Target: HT-1080
External Id: CHEMBL4733474

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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
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External Id: MCF7_OneDose

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Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600

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Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Name: Late stage results from the probe development effort to identify inhibitors of NOX1: ...
Source: The Scripps Research Institute Molecular Screening Center
Target: NADPH oxidase 1 [Homo sapiens]
External Id: Nox1_INH_LUMI_96_3XIC50_HEK/293_Set 2

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Source: The Scripps Research Institute Molecular Screening Center
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External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

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Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN

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EINECS 202-145-7

2-(Trifluoromethyl)-10H-phenothiazine

2-(Triflouomethyl) phenothiazine

MFCD00005018