TG100713
Modify Date: 2024-01-07 11:17:59
TG100713 structure
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Common Name | TG100713 | ||
|---|---|---|---|---|
| CAS Number | 925705-73-3 | Molecular Weight | 254.247 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 646.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C12H10N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 344.8±34.3 °C | |
Use of TG100713TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1]. |
| Name | 3-(2,4-diaminopteridin-6-yl)phenol |
|---|---|
| Synonym | More Synonyms |
| Description | TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1]. |
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| Related Catalog | |
| Target |
PI3Kδ:24 nM (IC50) PI3Kγ:50 nM (IC50) PI3Kα:165 nM (IC50) PI3Kβ:215 nM (IC50) |
| In Vitro | TG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 646.4±65.0 °C at 760 mmHg |
| Molecular Formula | C12H10N6O |
| Molecular Weight | 254.247 |
| Flash Point | 344.8±34.3 °C |
| Exact Mass | 254.091614 |
| PSA | 124.56000 |
| LogP | 0.50 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.815 |
| cc-655 |
| Phenol, 3-(2,4-diamino-6-pteridinyl)- |
| 3-(2,4-Diamino-6-pteridinyl)phenol |
| Phenol,3-(2,4-diamino-6-pteridinyl) |