HA-14-1

Modify Date: 2024-02-24 18:31:51

HA-14-1 Structure
HA-14-1 structure
Common Name HA-14-1
CAS Number 927635-64-1 Molecular Weight 409.231
Density 1.5±0.1 g/cm3 Boiling Point 535.1±50.0 °C at 760 mmHg
Molecular Formula C17H17BrN2O5 Melting Point N/A
MSDS N/A Flash Point 277.4±30.1 °C

 Use of HA-14-1


HA-14-1 is a small molecule that binds the surface pocket of Bcl-2 proteins (IC50 = ~ 9 M) and induces apoptosis by interfering with its interaction with the Bak peptide and activating Apaf-1 and caspase-9 and -3.

 Names

Name HA-14-1
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 535.1±50.0 °C at 760 mmHg
Molecular Formula C17H17BrN2O5
Molecular Weight 409.231
Flash Point 277.4±30.1 °C
Exact Mass 408.032074
LogP 3.70
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.574

 Synonyms

Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate
Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylic acid ethyl ester
MFCD00218213
MFCD22200055
HA14-1
HA-14-1
4H-1-Benzopyran-4-acetic acid, 2-amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-, ethyl ester
2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
HA 14-1