AZD-7295

Modify Date: 2025-08-21 19:29:16

Use of AZD-7295

AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].

Name	AZD-7295

Description	AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease Research Areas >> Inflammation/Immunology
References	[1]. Erik De Clercq, et al. Current race in the development of DAAs (direct-acting antivirals) against HCV. Biochem Pharmacol. 2014 Jun 15;89(4):441-52. [2]. Min Gao, et al. Antiviral activity and resistance of HCV NS5A replication complex inhibitors. Curr Opin Virol. 2013 Oct;3(5):514-20.

Description

AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease

Research Areas >> Inflammation/Immunology

References

Molecular Formula	C₃₂H₃₅F₃N₄O₅S
Molecular Weight	644.70
InChIKey	MAQDQJWCSSCURR-UHFFFAOYSA-N
SMILES	CCCS(=O)(=O)N1CCN(Cc2ccc(NC(=O)c3ccc(-c4cc(NC(=O)C5CC5)ccc4OC(F)(F)F)cc3)cc2)CC1

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