azetidinone
azetidinone structure
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Common Name | azetidinone | ||
|---|---|---|---|---|
| CAS Number | 930-21-2 | Molecular Weight | 71.078 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 222.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C3H5NO | Melting Point | 74-76 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 151.5±3.4 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | azetidin-2-one |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 222.4±0.0 °C at 760 mmHg |
| Melting Point | 74-76 °C(lit.) |
| Molecular Formula | C3H5NO |
| Molecular Weight | 71.078 |
| Flash Point | 151.5±3.4 °C |
| Exact Mass | 71.037117 |
| PSA | 29.10000 |
| LogP | -2.02 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.458 |
| InChIKey | MNFORVFSTILPAW-UHFFFAOYSA-N |
| SMILES | O=C1CCN1 |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C: Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 3263 8/PG 2 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2933790090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:107-95-9
CAS#:28562-53-0
CAS#:4138-35-6
CAS#:130065-29-1
CAS#:110967-04-9
CAS#:2679-13-2
CAS#:115946-47-9
CAS#:924-73-2
CAS#:925-90-6
CAS#:85270-00-4
CAS#:504-88-1
CAS#:81721-87-1
CAS#:153357-31-4
CAS#:5755-07-7
CAS#:682341-17-9![(3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone structure](https://image.chemsrc.com/caspic/357/149140-54-5.png)
CAS#:149140-54-5
CAS#:1140510-99-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933790090 |
|---|---|
| Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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The influence of ezetimibe on classical and alternative activation pathways of monocytes/macrophages isolated from patients with hypercholesterolemia.
Naunyn Schmiedebergs Arch. Pharmacol. 387(8) , 733-42, (2014) Macrophages are crucial for the development of atherosclerotic plaques. Classically activated macrophages contribute to plaque growth and destabilization, while alternatively activated macrophages inc... |
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Non-transpeptidase binding arylthioether β-lactams active against Mycobacterium tuberculosis and Moraxella catarrhalis.
Bioorg. Med. Chem. 23(3) , 632-47, (2015) The prevalence of drug resistance in both clinical and community settings as a consequence of alterations of biosynthetic pathways, enzymes or cell wall architecture is a persistent threat to human he... |
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Photoelectron spectra of some antibiotic building blocks: 2-azetidinone and thiazolidine-carboxylic acid.
J. Phys. Chem. A 116(33) , 8653-60, (2012) X-ray photoelectron spectra of the core and valence levels of the fundamental building blocks of β-lactam antibiotics have been investigated and compared with theoretical calculations. The spectra of ... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antimicrobial activity against Mycobacterium tuberculosis H37Rv incubated for 48 hrs ...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL3396596
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Name: Compound was evaluated for rate of hydrolysis expressed in hours at a pH of 12.
Source: ChEMBL
Target: N/A
External Id: CHEMBL642395
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Name: Compound was evaluated for the second order hydrolysis rate constant
Source: ChEMBL
Target: N/A
External Id: CHEMBL638937
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Name: Antimicrobial activity against Moraxella catarrhalis clinical isolates incubated for ...
Source: ChEMBL
Target: Moraxella catarrhalis
External Id: CHEMBL3396594
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Name: Binding affinity to CRBN (unknown origin) assessed as inhibition constant by FRET ass...
Source: ChEMBL
Target: Protein cereblon
External Id: CHEMBL5340015
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Name: Bactericidal activity against Moraxella catarrhalis clinical isolates incubated for 4...
Source: ChEMBL
Target: Moraxella catarrhalis
External Id: CHEMBL3396595
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| azetidinone |
| 2-AZACYCLOBUTANONE |
| 2-oxoazetidine |
| MFCD00013328 |
| AZETAN-2-ONE |
| 2-Azetidinone |
| Azetidin-2-one |
| 4-oxo-azetidine |
| Propiolactam |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of azetidin-2-one? |
| A: Molecular formula of azetidin-2-one is C3H5NO. |
| Q: What is the polar surface area (PSA) of azetidin-2-one? |
| A: Polar surface area (PSA) of azetidin-2-one is 29.10000. |
| Q: What is the CAS number of azetidin-2-one? |
| A: CAS number of azetidin-2-one is 930-21-2. |
| Q: What are the downstream products of azetidin-2-one? |
| A: Related downstream products(CAS) of azetidin-2-one: 504-88-1;81721-87-1;28562-53-0;153357-31-4;5755-07-7;682341-17-9;107-95-9;149140-54-5;115946-47-9;1140510-99-1. |
| Q: What is the safety information for azetidin-2-one? |
| A: Safety information for azetidin-2-one: S26-S36/37/39-S45. |
| Q: What is the boiling point of azetidin-2-one? |
| A: Boiling point of azetidin-2-one is 222.4±0.0 °C at 760 mmHg. |
| Q: What is the SMILES notation of azetidin-2-one? |
| A: SMILES notation of azetidin-2-one is O=C1CCN1. |
| Q: What are the storage conditions for azetidin-2-one? |
| A: Storage conditions for azetidin-2-one: 2-8°C. |
| Q: What are the upstream materials of azetidin-2-one? |
| A: Related upstream materials(CAS) of azetidin-2-one: 107-95-9;28562-53-0;4138-35-6;130065-29-1;110967-04-9;2679-13-2;115946-47-9;924-73-2;925-90-6;85270-00-4. |
| Q: What English synonyms does azetidin-2-one have? |
| A: English synonyms of azetidin-2-one: azetidinone, 2-AZACYCLOBUTANONE, 2-oxoazetidine, MFCD00013328, AZETAN-2-ONE, 2-Azetidinone, Azetidin-2-one, 4-oxo-azetidine, Propiolactam. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |