TG-46

Modify Date: 2024-07-18 17:58:22

TG-46 Structure
TG-46 structure
Common Name TG-46
CAS Number 936091-15-5 Molecular Weight 510.652
Density 1.3±0.1 g/cm3 Boiling Point 687.5±65.0 °C at 760 mmHg
Molecular Formula C26H34N6O3S Melting Point N/A
MSDS N/A Flash Point 369.6±34.3 °C

 Use of TG-46


JAK-IN-35 (compound TG46) is a JAK2 inhibitor that canb be used in cancer research[1].

 Names

Name N-tert-butyl-3-[[5-methyl-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
Synonym More Synonyms

 TG-46 Biological Activity

Description JAK-IN-35 (compound TG46) is a JAK2 inhibitor that canb be used in cancer research[1].
Related Catalog
References

[1]. Wenge Zhu, et al. Combination therapy for treating cancer. Patent WO2018187485A1.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 687.5±65.0 °C at 760 mmHg
Molecular Formula C26H34N6O3S
Molecular Weight 510.652
Flash Point 369.6±34.3 °C
Exact Mass 510.241302
PSA 120.09000
LogP 1.83
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.621

 Synonyms

EX-8668
RS0111
3-[(5-Methyl-2-{[4-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]-N-(2-methyl-2-propanyl)benzenesulfonamide
Benzenesulfonamide,N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]
Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-
N-tert-butyl-3-(5-methyl-2-(4-(morpholinomethyl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
TG-46
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