(3S,5R)-Fluvastatin sodium

Modify Date: 2024-01-10 19:16:03

(3S,5R)-Fluvastatin sodium Structure
(3S,5R)-Fluvastatin sodium structure
Common Name (3S,5R)-Fluvastatin sodium
CAS Number 94061-81-1 Molecular Weight 434.45600
Density N/A Boiling Point N/A
Molecular Formula C24H25FNNaO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (3S,5R)-Fluvastatin sodium


(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].

 Names

Name 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt , (3S,5R,6E)
Synonym More Synonyms

 (3S,5R)-Fluvastatin sodium Biological Activity

Description (3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].
Related Catalog
References

[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.

 Chemical & Physical Properties

Molecular Formula C24H25FNNaO4
Molecular Weight 434.45600
Exact Mass 434.17400
PSA 82.69000
LogP 4.62810

 Synonyms

(3S,5R)-Fluvastatin Sodium Salt
6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3S,5R,6E)-
6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R-[R*,S*-(E)]]-