Mycro 3

Modify Date: 2024-01-07 18:04:34

Mycro 3 Structure
Mycro 3 structure
Common Name Mycro 3
CAS Number 944547-46-0 Molecular Weight 526.879
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C24H17ClF2N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mycro 3


Mycro 3 is potent and selective for c-Myc in whole cell assays.

 Names

Name Mycro-3
Synonym More Synonyms

 Mycro 3 Biological Activity

Description Mycro 3 is potent and selective for c-Myc in whole cell assays.
Related Catalog
Target

c-Myc[1]

In Vitro Mycro 3 is potent and selective for c-Myc in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1), Mycro 3 has a superior specificity profile to its predecessors. Mycro 3 inhibits the interaction between c-Myc and Max. Mycro 3 has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA[1].
References

[1]. Chen BJ, et al. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci. 2014 Sep 13;10(10):1084-96.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C24H17ClF2N6O4
Molecular Weight 526.879
Exact Mass 526.096802
LogP 5.52
Appearance of Characters light yellow solid
Index of Refraction 1.680
Storage condition -20℃

 Synonyms

1H-Pyrazole-4-carboxylic acid, 5-[[[7-(chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-, ethyl ester
Ethyl 5-[({7-[chloro(difluoro)methyl]-5-(2-furyl)pyrazolo[1,5-a]pyrimidin-2-yl}carbonyl)amino]-1-phenyl-1H-pyrazole-4-carboxylate
Mycro 3