944547-46-0
944547-46-0 structure
- Name: Mycro 3
- Chemical Name: Mycro-3
- CAS Number: 944547-46-0
- Molecular Formula: C24H17ClF2N6O4
- Molecular Weight: 526.879
- Catalog: Signaling Pathways Apoptosis c-Myc
- Create Date: 2018-06-27 10:13:44
- Modify Date: 2024-01-07 18:04:34
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Mycro 3 is potent and selective for c-Myc in whole cell assays.
| Name | Mycro-3 |
|---|---|
| Synonyms |
1H-Pyrazole-4-carboxylic acid, 5-[[[7-(chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-, ethyl ester
Ethyl 5-[({7-[chloro(difluoro)methyl]-5-(2-furyl)pyrazolo[1,5-a]pyrimidin-2-yl}carbonyl)amino]-1-phenyl-1H-pyrazole-4-carboxylate Mycro 3 |
| Description | Mycro 3 is potent and selective for c-Myc in whole cell assays. |
|---|---|
| Related Catalog | |
| Target |
c-Myc[1] |
| In Vitro | Mycro 3 is potent and selective for c-Myc in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1), Mycro 3 has a superior specificity profile to its predecessors. Mycro 3 inhibits the interaction between c-Myc and Max. Mycro 3 has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C24H17ClF2N6O4 |
| Molecular Weight | 526.879 |
| Exact Mass | 526.096802 |
| LogP | 5.52 |
| Appearance | light yellow solid |
| Index of Refraction | 1.680 |
| Storage condition | -20℃ |