FG-3019

Modify Date: 2024-01-03 17:21:10

FG-3019 Structure
FG-3019 structure
Common Name FG-3019
CAS Number 946415-13-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FG-3019


FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2].

 Names

Name FG-3019

 FG-3019 Biological Activity

Description FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2].
Related Catalog
In Vivo FG-3019 (30 mg/kg; i.p. every 3 d for 9 d) 与 Gemcitabine 联合使用可显着降低小鼠胰腺导管腺癌 (PDA) 的生长,并诱导 LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) 小鼠中的肿瘤细胞凋亡[2]。
References

[1]. Sgalla G, et, al. Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug;29(8):771-777.  

[2]. Neesse A, et, al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties