J9
Modify Date: 2024-04-09 22:29:02
J9 structure
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Common Name | J9 | ||
|---|---|---|---|---|
| CAS Number | 947018-15-7 | Molecular Weight | 212.251 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 449.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C12H12N4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 256.3±18.7 °C | |
Use of J9J9 is a small molecule that reverses Dexamethasone (HY-14648) resistance in T-cell acute lymphoblastic leukemia. J9 is lethal to CUTLL1 cells only in the presence of Dexamethasone. J9 inhibits CUTLL1 cell growth with an EC50 of 28 μM in combination with Dexamethasone[1]. |
| Name | Glucocorticoid Resistance Inhibitor |
|---|---|
| Synonym | More Synonyms |
| Description | J9 is a small molecule that reverses Dexamethasone (HY-14648) resistance in T-cell acute lymphoblastic leukemia. J9 is lethal to CUTLL1 cells only in the presence of Dexamethasone. J9 inhibits CUTLL1 cell growth with an EC50 of 28 μM in combination with Dexamethasone[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.7±55.0 °C at 760 mmHg |
| Molecular Formula | C12H12N4 |
| Molecular Weight | 212.251 |
| Flash Point | 256.3±18.7 °C |
| Exact Mass | 212.106201 |
| LogP | 1.28 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.668 |
| 2-Pyrimidinamine, 4-cyclopropyl-5-(4-pyridinyl)- |
| Glucocorticoid Resistance Inhibitor |
| MFCD11051713 |
| 4-Cyclopropyl-5-(4-pyridinyl)-2-pyrimidinamine |