Sulbactam-d2 sodium

Modify Date: 2024-01-01 18:48:37

Sulbactam-d2 sodium structure	Common Name	Sulbactam-d2 sodium
	CAS Number	948027-82-5	Molecular Weight	257.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈H₈D₂NNaO₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sulbactam-d2 sodium

Sulbactam-d2 (sodium) is the deuterium labeled Sulbactam sodium[1]. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[2][3].

Name	Sulbactam-d2 sodium

Description	Sulbactam-d2 (sodium) is the deuterium labeled Sulbactam sodium[1]. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Noguchi JK, et al. Sulbactam: a beta-lactamase inhibitor. Clin Pharm. 1988;7(1):37-51. [3]. Lin HS, et al. Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Infect Dis (Lond). 201547(6):370-378. [4]. Betrosian AP, et al. Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections. Expert Opin Drug Metab Toxicol. 20095(9):1099-1112.

Molecular Formula	C₈H₈D₂NNaO₅S
Molecular Weight	257.24

Sulbactam-d2 sodium

Use of Sulbactam-d2 sodium

Names

Sulbactam-d2 sodium Biological Activity

Chemical & Physical Properties