2,4-Xylidine

Modify Date: 2024-01-02 17:52:41

2,4-Xylidine Structure
2,4-Xylidine structure
Common Name 2,4-Xylidine
CAS Number 95-68-1 Molecular Weight 121.180
Density 1.0±0.1 g/cm3 Boiling Point 214.7±9.0 °C at 760 mmHg
Molecular Formula C8H11N Melting Point 16 °C
MSDS Chinese USA Flash Point 90.6±0.0 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Names

Name 2,4-dimethylaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 214.7±9.0 °C at 760 mmHg
Melting Point 16 °C
Molecular Formula C8H11N
Molecular Weight 121.180
Flash Point 90.6±0.0 °C
Exact Mass 121.089149
PSA 26.02000
LogP 1.86
Vapour density 4.2 (vs air)
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.559
Stability Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides, chloroformates, halogens.
Water Solubility 5 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE8925000
CHEMICAL NAME :
2,4-Xylidine
CAS REGISTRY NUMBER :
95-68-1
BEILSTEIN REFERENCE NO. :
0636243
LAST UPDATED :
199806
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
ZR B1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
467 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
149 ppm/7H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1170 mg/kg/10D-C
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13300 mg/kg/4W-I
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
TYPE OF TEST :
DNA damage

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,367,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,367,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301 + H311 + H331-H373-H411
Precautionary Statements Missing Phrase - N15.00950417-P260-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/24/25;R33;R51/53
Safety Phrases S28-S36/37-S45-S61-S28A
RIDADR UN 1711 6.1/PG 2
WGK Germany 2
RTECS ZE8925000
Packaging Group II
Hazard Class 6.1
HS Code 2921419000

 Synthetic Route

 Customs

HS Code 2921419000
Summary 2921419000 aniline and its salts。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

2,4-Dimethylaniline
EINECS 202-440-0
2,4-Xylidine
Benzenamine, 2,4-dimethyl-
4-Amino-1,3-xylene
MFCD00007738
2,4-Dimethyl aniline
4-Amino-1,3-dimethylbenzene
aniline, 2,4-dimethyl-
1-Amino-2,4-dimethylbenzene
2,4-dimethylphenylamine
2,4-dimethyl-Benzenamine
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