2-Amino-4-chlorophenol

Modify Date: 2024-01-03 00:23:33

2-Amino-4-chlorophenol Structure
2-Amino-4-chlorophenol structure
Common Name 2-Amino-4-chlorophenol
CAS Number 95-85-2 Molecular Weight 143.571
Density 1.4±0.1 g/cm3 Boiling Point 276.8±25.0 °C at 760 mmHg
Molecular Formula C6H6ClNO Melting Point 136-141 °C(lit.)
MSDS Chinese USA Flash Point 121.2±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Amino-4-chlorophenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 276.8±25.0 °C at 760 mmHg
Melting Point 136-141 °C(lit.)
Molecular Formula C6H6ClNO
Molecular Weight 143.571
Flash Point 121.2±23.2 °C
Exact Mass 143.013794
PSA 46.25000
LogP 1.67
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.651
Water Solubility Insoluble.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SJ5700000
CHEMICAL NAME :
Phenol, 2-amino-4-chloro-
CAS REGISTRY NUMBER :
95-85-2
BEILSTEIN REFERENCE NO. :
0774859
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H6-Cl-N-O
MOLECULAR WEIGHT :
143.58
WISWESSER LINE NOTATION :
ZR BQ EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
690 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1030 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
333 ug/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82099 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S36/37/39
RIDADR UN 2673 6.1/PG 2
WGK Germany 3
RTECS SJ5700000
Packaging Group II
Hazard Class 6.1
HS Code 29222900

 Synthetic Route

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles12

More Articles
Metabolism of 4-chloro-2-nitrophenol in a gram-positive bacterium, Exiguobacterium sp. PMA.

Microb. Cell Fact. 11 , 150, (2012)

Chloronitrophenols (CNPs) are widely used in the synthesis of dyes, drugs and pesticides, and constitute a major group of environmental pollutants. 4-Chloro-2-nitrophenol (4C2NP) is an isomer of CNPs ...

A new way for synthesis of phenoxazine and diphenoxazine derivatives via electrochemical method.

Chem. Pharm. Bull. 59(10) , 1209-13, (2011)

Electrochemical oxidation of hydroquinone (1a) and 2,3-dimethylhydroquinone (1b) have been studied in the presence of 2-aminophenol (3a) and 2-amino-4-chlorophenol (3b), as nucleophiles in phosphate b...

Stability-indicating TLC-densitometric method for simultaneous determination of paracetamol and chlorzoxazone and their toxic impurities.

J. Chromatogr. Sci. 51(2) , 187-91, (2013)

A highly sensitive, selective and accurate thin-layer chromatographic (TLC)-densitometric method has been developed and validated for the simultaneous determination of paracetamol (PAR) and chlorzoxaz...

 Synonyms

EINECS 202-458-9
2-Amino-4-chlorophenol
5-Chloro-2-hydroxyaniline
Phenol, 2-amino-4-chloro-
MFCD00007694
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