2-Amino-4-chlorophenol
2-Amino-4-chlorophenol structure
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Common Name | 2-Amino-4-chlorophenol | ||
|---|---|---|---|---|
| CAS Number | 95-85-2 | Molecular Weight | 143.571 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 276.8±25.0 °C at 760 mmHg | |
| Molecular Formula | C6H6ClNO | Melting Point | 136-141 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 121.2±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metabolism of 4-chloro-2-nitrophenol in a gram-positive bacterium, Exiguobacterium sp. PMA.
Microb. Cell Fact. 11 , 150, (2012) Chloronitrophenols (CNPs) are widely used in the synthesis of dyes, drugs and pesticides, and constitute a major group of environmental pollutants. 4-Chloro-2-nitrophenol (4C2NP) is an isomer of CNPs that has been detected in various industrial effluents. A n... |
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A new way for synthesis of phenoxazine and diphenoxazine derivatives via electrochemical method.
Chem. Pharm. Bull. 59(10) , 1209-13, (2011) Electrochemical oxidation of hydroquinone (1a) and 2,3-dimethylhydroquinone (1b) have been studied in the presence of 2-aminophenol (3a) and 2-amino-4-chlorophenol (3b), as nucleophiles in phosphate buffer solution (pH 7.2) using cyclic voltammetry and contro... |
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Stability-indicating TLC-densitometric method for simultaneous determination of paracetamol and chlorzoxazone and their toxic impurities.
J. Chromatogr. Sci. 51(2) , 187-91, (2013) A highly sensitive, selective and accurate thin-layer chromatographic (TLC)-densitometric method has been developed and validated for the simultaneous determination of paracetamol (PAR) and chlorzoxazone (CZ) and their toxic impurities, 4-amino phenol (4AP) a... |
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Nephrotoxicity of 4-amino-2-chlorophenol and 2-amino-4-chlorophenol in the Fischer 344 rat.
Toxicology 110(1-3) , 47-58, (1996) Aminophenols and halogenated anilines induce nephrotoxicity and mild hepatotoxicity in rats. In this study, the in vivo and in vitro nephrotoxic potential of 4-amino-2-chlorophenol and 2-amino-4-chlorophenol, monochlorinated aminophenols and potential metabol... |
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5-Chloro-2-hydroxyaniline-copper(II) coprecipitation system for preconcentration and separation of lead(II) and chromium(III) at trace levels.
J. Hazard. Mater. 158(1) , 137-41, (2008) A separation-preconcentration procedure based on the coprecipitation of lead(II) and chromium(III) ions with copper(II)-5-chloro-2-hydroxyaniline system has been developed. Effects of pH, sample volume and interferences on the recovery of the metal ions were ... |
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Industrial contact dermatitis due to nitro and amino derivatives. 2nd report: experimental study of cross sensitivities of amino derivatives.
J. Dermatol. 9(5) , 367-73, (1982)
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Kinetic study of alkaline induced hydrolysis of the skeletal muscle relaxant chlorzoxazone using ratio spectra first derivative spectrophotometry.
Il Farmaco 58(4) , 337-42, (2003) 2-Amino-4-chlorophenol was found to be the alkaline induced degradation product and the synthetic precursor of chlorzoxazone. The aim of this work is to study different factors affecting the degradation process due to the high toxicity of 2-amino-4-chlorophen... |
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Decolourization of 4-chloro-2-nitrophenol by a soil bacterium, Bacillus subtilis RKJ 700.
PLoS ONE 7(12) , e52012, (2012) A 4-Chloro-2-nitrophenol (4C2NP) decolourizing strain RKJ 700 was isolated from soil collected from a pesticide contaminated site of India and identified as Bacillus subtilis on the basis of the 16S rRNA gene sequence analysis. Bacillus subtilis RKJ 700 decol... |
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Small molecule inhibitors of lysozyme amyloid aggregation.
Cell Biochem. Biophys. 44(3) , 549-53, (2006) Protein amyloid aggregation is associated with a number of important human pathologies, but the precise mechanisms underlying the toxicity of amyloid aggregates are still incompletely understood. In this context, drugs capable of blocking or interfering with ... |
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Spectroscopic (FT-IR/FT-Raman) and computational (HF/DFT) investigation and HOMO/LUMO/MEP analysis on 2-amino-4-chlorophenol.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 104 , 337-51, (2013) The spectra (FT-IR and FT-Raman) of the present compound; 2-amino-4-chlorophenol (2A4CP) were recorded in the range of 4000-100 cm(-1). All the computational calculations were made in the ground state using the HF and DFT (B3LYP and B3PW91) methods with 6-31+... |