Isolinderalactone

Modify Date: 2024-01-03 12:11:16

Isolinderalactone structure	Common Name	Isolinderalactone
	CAS Number	957-66-4	Molecular Weight	244.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Isolinderalactone

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells[1]. Isolinderalactone suppresses the expression of B-cell lymphoma 2 (Bcl-2), survi

Name	(3aS,8bR)-4,8-dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one
Synonym	More Synonyms

Description	Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells[1]. Isolinderalactone suppresses the expression of B-cell lymphoma 2 (Bcl-2), survi
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Survivin Signaling Pathways >> Apoptosis >> IAP Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR2 Bcl-2
References	[1]. Park JH, et al. Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models. Cancer Lett. 2020;478:71-81. [2]. Hwang JY, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model. Cancer Lett. 2019;443:25-33.