Charybdotoxin
Charybdotoxin structure
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Common Name | Charybdotoxin | ||
|---|---|---|---|---|
| CAS Number | 95751-30-7 | Molecular Weight | 4295.89 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C176H277N57O55S7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of CharybdotoxinCharybdotoxin, a 37-amino acid peptide isolated from venom of the scorpion Leiurus quinquestriatus var. hebraeus, is a K+ channel blocker[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Charybdotoxin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Charybdotoxin, a 37-amino acid peptide isolated from venom of the scorpion Leiurus quinquestriatus var. hebraeus, is a K+ channel blocker[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Charybdotoxin represents a remarkable tool for studying K+ channels[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C176H277N57O55S7 |
|---|---|
| Molecular Weight | 4295.89 |
| InChIKey | CNVQLPPZGABUCM-LIGYZCPXSA-N |
| SMILES | CSCCC1NC(=O)C2CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(Cc3ccccc3)NC(=O)C3CCC(=O)N3)C(C)O)C(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC3CSSCC(NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC(N)=O)NC1=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CO)C(=O)O)CSSCC(NC(=O)C(C(C)C)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c4ccccc14)NC3=O)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCCN)C(=O)N2 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Triclosan, an environmental pollutant from health care products, evokes charybdotoxin-sensitive hyperpolarization in rat thymocytes.
Environ. Toxicol. Pharmacol. 32(3) , 417-22, (2011) The effects of triclosan, an environmental pollutant from household items and health care products, on membrane potential and intracellular Ca(2+) concentrations of rat thymocytes were examined by a f... |
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Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.
Life Sci. 92(23) , 1131-7, (2013) Rheumatoid arthritis (RA) is associated with high cardiovascular mortality. Impaired endothelial cell (EC) function and elevated angiotensin II levels may be central to the link between vascular dysfu... |
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The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Am. J. Physiol. Lung Cell. Mol. Physiol. 303(11) , L956-66, (2012) Activation of taste receptors (TAS2Rs) by bitter taste agonists has been reported to cause bronchodilation. The aim of this study was to extend the information on the effects of bitter taste agonists ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00146378 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of Charybdotoxin? |
| A: InChIKey of Charybdotoxin is CNVQLPPZGABUCM-LIGYZCPXSA-N. |
| Q: What is the CAS number of Charybdotoxin? |
| A: CAS number of Charybdotoxin is 95751-30-7. |
| Q: What English synonyms does Charybdotoxin have? |
| A: English synonyms of Charybdotoxin: MFCD00146378. |
| Q: What are the uses of Charybdotoxin? |
| A: Main uses of Charybdotoxin: Charybdotoxin, a 37-amino acid peptide isolated from venom of the scorpion Leiurus quinquestriatus var. hebraeus, is a K+ channel blocker[1]. |
| Q: What is the molecular formula of Charybdotoxin? |
| A: Molecular formula of Charybdotoxin is C176H277N57O55S7. |
| Q: What is the molecular weight of Charybdotoxin? |
| A: Molecular weight of Charybdotoxin is 4295.89. |
| Q: What is the English name of Charybdotoxin? |
| A: The English name of Charybdotoxin is Charybdotoxin. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |