Charybdotoxin

Modify Date: 2024-01-02 15:16:43

Charybdotoxin structure	Common Name	Charybdotoxin
	CAS Number	95751-30-7	Molecular Weight	4295.89
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇₆H₂₇₇N₅₇O₅₅S₇	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Charybdotoxin

Charybdotoxin, a 37-amino acid peptide isolated from venom of the scorpion Leiurus quinquestriatus var. hebraeus, is a K+ channel blocker[1].

Name	Charybdotoxin
Synonym	More Synonyms

Description	Charybdotoxin, a 37-amino acid peptide isolated from venom of the scorpion Leiurus quinquestriatus var. hebraeus, is a K+ channel blocker[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In Vitro	Charybdotoxin represents a remarkable tool for studying K+ channels[1].
References	[1]. M L Garcia , et al. Charybdotoxin and its effects on potassium channels. Am J Physiol. 1995 Jul;269(1 Pt 1):C1-10.

Molecular Formula	C₁₇₆H₂₇₇N₅₇O₅₅S₇
Molecular Weight	4295.89

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

Triclosan, an environmental pollutant from health care products, evokes charybdotoxin-sensitive hyperpolarization in rat thymocytes.

Environ. Toxicol. Pharmacol. 32(3) , 417-22, (2011)

The effects of triclosan, an environmental pollutant from household items and health care products, on membrane potential and intracellular Ca(2+) concentrations of rat thymocytes were examined by a f...

Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.

Life Sci. 92(23) , 1131-7, (2013)

Rheumatoid arthritis (RA) is associated with high cardiovascular mortality. Impaired endothelial cell (EC) function and elevated angiotensin II levels may be central to the link between vascular dysfu...

The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.

Am. J. Physiol. Lung Cell. Mol. Physiol. 303(11) , L956-66, (2012)

Activation of taste receptors (TAS2Rs) by bitter taste agonists has been reported to cause bronchodilation. The aim of this study was to extend the information on the effects of bitter taste agonists ...

MFCD00146378