Oxychlorpromazine
Oxychlorpromazine structure
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Common Name | Oxychlorpromazine | ||
|---|---|---|---|---|
| CAS Number | 969-99-3 | Molecular Weight | 334.86400 | |
| Density | 1.35g/cm3 | Boiling Point | 502.6ºC at 760 mmHg | |
| Molecular Formula | C17H19ClN2OS | Melting Point | 115° | |
| MSDS | N/A | Flash Point | 257.8ºC | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 502.6ºC at 760 mmHg |
| Melting Point | 115° |
| Molecular Formula | C17H19ClN2OS |
| Molecular Weight | 334.86400 |
| Flash Point | 257.8ºC |
| Exact Mass | 334.09100 |
| PSA | 42.76000 |
| LogP | 4.84060 |
| Index of Refraction | 1.687 |
| InChIKey | QEPPAOXKZOTMPM-UHFFFAOYSA-N |
| SMILES | CN(C)CCCN1c2ccccc2S(=O)c2ccc(Cl)cc21 |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Detail
Learn More
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| Literature: Slavik, Roger; Peters, Jens-Uwe; Giger, Rudolf; Buerkler, Markus; Bald, Eric Tetrahedron Letters, 2011 , vol. 52, # 7 p. 749 - 752 |
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~91%
Oxychlorpromazine CAS#:969-99-3 |
| Literature: Owens; Juenge; Poklis Journal of Pharmaceutical Sciences, 1989 , vol. 78, # 4 p. 334 - 336 |
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~83%
Oxychlorpromazine CAS#:969-99-3 |
| Literature: Stalder, Romain; Roth, Gregory P. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 11 p. 1119 - 1123 |
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~99%
Oxychlorpromazine CAS#:969-99-3 |
| Literature: Bosch, Eric; Kochi, Jay K. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 8 p. 1057 - 1064 |
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Oxychlorpromazine CAS#:969-99-3 |
| Literature: Kano; Fujimoto Pharmaceutical Bulletin, 1957 , vol. 5, p. 393,396 |
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Oxychlorpromazine CAS#:969-99-3 |
| Literature: Wisniewska, Joanna; Rzesnicki, Pawel; Topolski, Adrian Transition Metal Chemistry, 2011 , vol. 36, # 7 p. 767 - 774 |
![10H-Phenothiazin-3-ol,8-chloro-10-[3-(dimethylamino)propyl] structure](https://image.chemsrc.com/caspic/153/2095-62-7.png)
![2-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-1-ol structure](https://image.chemsrc.com/caspic/137/3926-66-7.png)
![2-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-3-ol structure](https://image.chemsrc.com/caspic/488/3930-47-0.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 1 | |
This table lists relevant public references with title, journal and publication metadata for this compound.
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[Simultaneous determination of chlorpromazine and promethazine and their main metabolites by capillary electrophoresis with electrochemiluminescence].
Se Pu 30(9) , 938-42, (2012) Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) inte... |
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Free radical production by chlorpromazine sulfoxide, an ESR spin-trapping and flash photolysis study.
Photochem. Photobiol. 44(1) , 5-10, (1986)
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Involvement of erythrocyte skeletal proteins in the modulation of membrane fluidity by phenothiazines.
Biochemistry 26(25) , 8133-7, (1987) The effects of phenothiazines (chlorpromazine, chlorpromazine sulfoxide, and trifluoperazine) and antimitotic drugs (colchicine and vinblastine) on the erythrocyte membrane have been investigated. Chl... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antitubercular activity against Mycobacterium smegmatis by checkerboard assay
Source: ChEMBL
Target: Mycolicibacterium smegmatis
External Id: CHEMBL3364027
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Name: Anti MDR activity was expressed as MDR ratio or MDR fold reversal in doxorubicin resi...
Source: ChEMBL
Target: MCF7-DOX
External Id: CHEMBL710914
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Name: Inhibitory activity against human erythrocyte glutathione reductase; '*' indicates No...
Source: ChEMBL
Target: Glutathione reductase, mitochondrial
External Id: CHEMBL685506
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Name: Antitubercular activity against Mycobacterium smegmatis by checkerboard assay in pres...
Source: ChEMBL
Target: Mycolicibacterium smegmatis
External Id: CHEMBL3364030
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Name: Antimycobacterial against Mycobacterium smegmatis
Source: ChEMBL
Target: Mycolicibacterium smegmatis
External Id: CHEMBL3227835
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Name: Antitubercular activity against Mycobacterium smegmatis by checkerboard assay in pres...
Source: ChEMBL
Target: Mycolicibacterium smegmatis
External Id: CHEMBL3364031
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Name: Inhibition of binding of Batrachotoxinin [3H]BTX-B to high-affinity sites on voltage-...
Source: ChEMBL
Target: Sodium channel protein type 3 subunit alpha
External Id: CHEMBL806154
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Name: Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage ...
Source: ChEMBL
Target: Sodium channel protein type 3 subunit alpha
External Id: CHEMBL806153
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Name: Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypano...
Source: ChEMBL
Target: Trypanothione reductase
External Id: CHEMBL811879
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Name: TREK1 Assay from Article 10.1111/cbdd.12810: "Identification of the first in silico-d...
Source: BindingDB
Target: N/A
External Id: BindingDB_7564_1
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Chlorpromazine sulphoxide |
| Opromazine |
| Chlorpromazine-S-oxyd |
| Oxychlorpromazine |
| Chloropromazine sulfoxide |
| Opromazin |
| Transedon |
| Chlorpromazine sulfoxide |
| Chlorpromazine-S-oxide |
| Secotil |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Polar surface area (PSA) of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is 42.76000. |
| Q: What is the CAS number of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: CAS number of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is 969-99-3. |
| Q: What is the molecular formula of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Molecular formula of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is C17H19ClN2OS. |
| Q: What is the molecular weight of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Molecular weight of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is 334.86400. |
| Q: What are the downstream products of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Related downstream products(CAS) of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine: 50-53-3. |
| Q: What is the melting point of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Melting point of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is 115°. |
| Q: What are the upstream materials of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: Related upstream materials(CAS) of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine: 50-53-3;130-61-0;69-09-0;109-54-6. |
| Q: What is the SMILES notation of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: SMILES notation of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is CN(C)CCCN1c2ccccc2S(=O)c2ccc(Cl)cc21. |
| Q: What is the InChIKey of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine? |
| A: InChIKey of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine is QEPPAOXKZOTMPM-UHFFFAOYSA-N. |
| Q: What English synonyms does 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine have? |
| A: English synonyms of 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine: Chlorpromazine sulphoxide, Opromazine, Chlorpromazine-S-oxyd, Oxychlorpromazine, Chloropromazine sulfoxide, Opromazin, Transedon, Chlorpromazine sulfoxide, Chlorpromazine-S-oxide, Secotil. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |