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氧氯丙嗪

更新时间:2025-08-25 21:18:57

氧氯丙嗪结构式
氧氯丙嗪结构式
品牌特惠专场
常用名 氧氯丙嗪 英文名 Oxychlorpromazine
CAS号 969-99-3 分子量 334.86400
密度 1.35g/cm3 沸点 502.6ºC at 760 mmHg
分子式 C17H19ClN2OS 熔点 115°
MSDS N/A 闪点 257.8ºC

 氧氯丙嗪名称

中文名 氧氯丙嗪
英文名 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
英文别名 更多

 氧氯丙嗪物理化学性质

密度 1.35g/cm3
沸点 502.6ºC at 760 mmHg
熔点 115°
分子式 C17H19ClN2OS
分子量 334.86400
闪点 257.8ºC
精确质量 334.09100
PSA 42.76000
LogP 4.84060
InChIKey QEPPAOXKZOTMPM-UHFFFAOYSA-N
SMILES CN(C)CCCN1c2ccccc2S(=O)c2ccc(Cl)cc21
折射率 1.687

 氧氯丙嗪毒性和生态

 氧氯丙嗪合成线路

~1%

详细
文献:Slavik, Roger; Peters, Jens-Uwe; Giger, Rudolf; Buerkler, Markus; Bald, Eric Tetrahedron Letters, 2011 , vol. 52, # 7 p. 749 - 752

~91%

氧氯丙嗪结构式

氧氯丙嗪

969-99-3

文献:Owens; Juenge; Poklis Journal of Pharmaceutical Sciences, 1989 , vol. 78, # 4 p. 334 - 336

~83%

氧氯丙嗪结构式

氧氯丙嗪

969-99-3

文献:Stalder, Romain; Roth, Gregory P. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 11 p. 1119 - 1123

~99%

氧氯丙嗪结构式

氧氯丙嗪

969-99-3

文献:Bosch, Eric; Kochi, Jay K. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 8 p. 1057 - 1064

~%

氧氯丙嗪结构式

氧氯丙嗪

969-99-3

文献:Kano; Fujimoto Pharmaceutical Bulletin, 1957 , vol. 5, p. 393,396

~%

氧氯丙嗪结构式

氧氯丙嗪

969-99-3

文献:Wisniewska, Joanna; Rzesnicki, Pawel; Topolski, Adrian Transition Metal Chemistry, 2011 , vol. 36, # 7 p. 767 - 774

 氧氯丙嗪文献25

更多文献
[Simultaneous determination of chlorpromazine and promethazine and their main metabolites by capillary electrophoresis with electrochemiluminescence].

Se Pu 30(9) , 938-42, (2012)

Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) inte...

Free radical production by chlorpromazine sulfoxide, an ESR spin-trapping and flash photolysis study.

Photochem. Photobiol. 44(1) , 5-10, (1986)

Involvement of erythrocyte skeletal proteins in the modulation of membrane fluidity by phenothiazines.

Biochemistry 26(25) , 8133-7, (1987)

The effects of phenothiazines (chlorpromazine, chlorpromazine sulfoxide, and trifluoperazine) and antimitotic drugs (colchicine and vinblastine) on the erythrocyte membrane have been investigated. Chl...

 氧氯丙嗪靶点实验

查看更多实验

实验名称:Antitubercular activity against Mycobacterium smegmatis by checkerboard assay
来源:ChEMBL
靶标:Mycolicibacterium smegmatis
External Id:CHEMBL3364027
实验名称:Anti MDR activity was expressed as MDR ratio or MDR fold reversal in doxorubicin resi...
来源:ChEMBL
靶标:MCF7-DOX
External Id:CHEMBL710914
实验名称:Inhibitory activity against human erythrocyte glutathione reductase; '*' indicates No...
来源:ChEMBL
靶标:Glutathione reductase, mitochondrial
External Id:CHEMBL685506
实验名称:Antitubercular activity against Mycobacterium smegmatis by checkerboard assay in pres...
来源:ChEMBL
靶标:Mycolicibacterium smegmatis
External Id:CHEMBL3364030
实验名称:Antimycobacterial against Mycobacterium smegmatis
来源:ChEMBL
靶标:Mycolicibacterium smegmatis
External Id:CHEMBL3227835
实验名称:Antitubercular activity against Mycobacterium smegmatis by checkerboard assay in pres...
来源:ChEMBL
靶标:Mycolicibacterium smegmatis
External Id:CHEMBL3364031
实验名称:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high-affinity sites on voltage-...
来源:ChEMBL
靶标:Sodium channel protein type 3 subunit alpha
External Id:CHEMBL806154
实验名称:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage ...
来源:ChEMBL
靶标:Sodium channel protein type 3 subunit alpha
External Id:CHEMBL806153
实验名称:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypano...
来源:ChEMBL
靶标:Trypanothione reductase
External Id:CHEMBL811879
实验名称:TREK1 Assay from Article 10.1111/cbdd.12810: "Identification of the first in silico-d...
来源:BindingDB
靶标:N/A
External Id:BindingDB_7564_1
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 氧氯丙嗪英文别名

Chlorpromazine sulphoxide
Opromazine
Chlorpromazine-S-oxyd
Oxychlorpromazine
Chloropromazine sulfoxide
Opromazin
Transedon
Chlorpromazine sulfoxide
Chlorpromazine-S-oxide
Secotil
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