2′-Deoxy-8-(phenylmethoxy)guanosine
Modify Date: 2024-01-14 16:36:15
2′-Deoxy-8-(phenylmethoxy)guanosine structure
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Common Name | 2′-Deoxy-8-(phenylmethoxy)guanosine | ||
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| CAS Number | 96964-90-8 | Molecular Weight | 373.36 | |
| Density | 1.708g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H19N5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2′-Deoxy-8-(phenylmethoxy)guanosine2′-Deoxy-8-(phenylmethoxy)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 2-amino-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-3H-purin-6-one |
|---|---|
| Synonym | More Synonyms |
| Description | 2′-Deoxy-8-(phenylmethoxy)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.708g/cm3 |
|---|---|
| Molecular Formula | C17H19N5O5 |
| Molecular Weight | 373.36 |
| Exact Mass | 373.13900 |
| PSA | 148.51000 |
| LogP | 0.50270 |
| Index of Refraction | 1.772 |
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~82%
2′-Deoxy-8-(phe... CAS#:96964-90-8 |
| Literature: Nampalli, Satyam; Kumar, Shiv Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1677 - 1679 |
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~78%
2′-Deoxy-8-(phe... CAS#:96964-90-8 |
| Literature: Nampalli, Satyam; Livshin, Inna; Kumar, Shiv Nucleosides and Nucleotides, 1999 , vol. 18, # 4-5 p. 697 - 699 |
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~%
2′-Deoxy-8-(phe... CAS#:96964-90-8 |
| Literature: Varaprasad, Chamakura V.; Bulychev, Nickolai; Grollman, Arthur P.; Johnson, Francis Tetrahedron Letters, 1996 , vol. 37, # 1 p. 9 - 12 |
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~%
2′-Deoxy-8-(phe... CAS#:96964-90-8 |
| Literature: Kannan, Arunkumar; Burrows, Cynthia J. Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 720 - 723 |
CAS#:88847-89-6
CAS#:139307-94-1| 8-Benzyloxy-2'-deoxyguanosine |
| 2'-Deoxy-8-(phenylmethoxy)guanosine |