4-Nitro-o-anisidine

Modify Date: 2024-01-02 15:48:03

4-Nitro-o-anisidine Structure
4-Nitro-o-anisidine structure
 Common Name 4-Nitro-o-anisidine
CAS Number 97-52-9 Molecular Weight 168.150
Density 1.3±0.1 g/cm3 Boiling Point 364.2±22.0 °C at 760 mmHg
Molecular Formula C7H8N2O3 Melting Point 140-142 °C(lit.)
MSDS Chinese USA Flash Point 174.0±22.3 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Names

Name 2-Methoxy-4-nitroaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 364.2±22.0 °C at 760 mmHg
Melting Point 140-142 °C(lit.)
Molecular Formula C7H8N2O3
Molecular Weight 168.150
Flash Point 174.0±22.3 °C
Exact Mass 168.053497
PSA 81.07000
LogP 1.85
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.601
Water Solubility slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ7170000
CHEMICAL NAME :
o-Anisidine, 4-nitro-
CAS REGISTRY NUMBER :
97-52-9
BEILSTEIN REFERENCE NO. :
0879619
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C7-H8-N2-O3
MOLECULAR WEIGHT :
168.17
WISWESSER LINE NOTATION :
WNR DZ C01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
997 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,717,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0147 No. of Facilities: 174 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 523 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0147 No. of Facilities: 70 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 198 (estimated) No. of Female Employees: 80 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22
Safety Phrases S26-S37/39-S36/37
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS BZ7170000
Hazard Class 6.1
HS Code 29222900

 Synthetic Route

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

More Articles
2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver.

Cancer Lett. 96(1) , 95-8, (1995)

Male F344 rats were treated with a chemical (aniline, nitrobenzene, 2-methoxy-p-phenylenediamine, 2-methoxy-4-nitroaniline or 2-methoxy-4-nitroazobenzene) produced by the azo-reduction and/or N-oxidat...

Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice.

Xenobiotica 42(12) , 1213-24, (2012)

The disposition of 2-Methoxy-4-nitroaniline (MNA) was investigated in male and female Harlan Sprague Dawley rats and B6C3F(1)/N mice following oral, intravenous, and dermal exposure to [(14)C]MNA at 2...

Use of nitroanilines for spectrophotometric determination of ethinylestradiol in pharmaceutical formulations. Leonardo SG, et al.

Anal. Methods 3(5) , 1198-1201, (2011)

 Synonyms

2-METHOXY-4-NITROANILINE/4-NITRO-O-ANISIDINE
EINECS 202-588-6
2-Amino-5-nitroanisole
2-amino-5-nitroanisol
2-methoxy-4nitro-aniline
4-Nitro-o-anisidine
KERNECHTROT SALT B
2-Methoxy-4-nitrobenzenamine
2-METHOXY-4-NITRO-ANILINE 97-52-9
2-Methoxy-4-nitroaniline
2-METHOXY-4-NITROANILINE FOR SYNTHESIS
Red B Base
2-methoxy-4-nitrophenylamine
1-amino-2-methoxy-4-nitrobenzene
Fast Red B
2-Amino-1-methoxy-5-nitrobenzene
2-METHOXY-4-NITROANILIN
4-Nitro-6-methoxyaniline
Benzenamine, 2-methoxy-4-nitro-
5-nitro-2-amino-1-methoxy-benzene
Fast Red Base B
Benzenamine,2-methoxy-4-nitro
o-Anisidine,4-nitro
2-METHOXY-4-NITRO ANILINE
5-Nitro-2-anisidine
5-nitro-2-amino-anisole
MFCD00007363
4-Amino-3-methoxynitrobenzene
4-NITRO-O-ANISIDINE (NH2=1)
Fast Red B Base
FASTREDBBASE
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