α-Me-5-HT
α-Me-5-HT structure
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Common Name | α-Me-5-HT | ||
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| CAS Number | 97469-12-0 | Molecular Weight | 306.31400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H18N2O5 | Melting Point | 191 - 193 °C | |
| MSDS | USA | Flash Point | N/A | |
Use of α-Me-5-HTα-methyl Serotonin (maleate) is an agonist of serotonin (5-HT) receptors. It binds selectively to 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1D receptors over 5-HT1E receptors. It is also selective for 5-HT2B and 5-HT2C receptors over 5-HT2A receptors. α-methyl Serotonin potentiates motor neuron depolarizations induced by NMDA in the presence of the NMDA receptor antagonist memantine. It also increases dopamine release in a dose-dependent manner. α-methyl Serotonin increases systolic blood pressure and transiently increases heart rate. |
| Name | 3-(2-aminopropyl)-1H-indol-5-ol,(Z)-but-2-enedioic acid |
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| Synonym | More Synonyms |
| Melting Point | 191 - 193 °C |
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| Molecular Formula | C15H18N2O5 |
| Molecular Weight | 306.31400 |
| Exact Mass | 306.12200 |
| PSA | 136.64000 |
| LogP | 2.17530 |
| Storage condition | 20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin.
J. Med. Chem. 33 , 755-758, (1990) alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were syn... |
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Serotonin via 5-HT1B and 5-HT2B receptors stimulates anion secretion in the rat epididymal epithelium.
J. Physiol. 519 , 519, (1999) 1. The short-circuit current (Isc) technique was used to study the role of 5-hydroxytryptamine (5-HT) in the regulation of anion secretion in cultured rat cauda epididymal epithelia. 2. 5-HT, the 5-HT... |
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Effects of serotonin-1 and serotonin-2 receptor agonists on neuronal activity in the nucleus tractus solitarius.
J. Auton. Nerv. Syst. 56 , 119-124, (1995) Spontaneous neuronal activity in the solitary tract nucleus was recorded extracellularly in a brain slice preparation during bath-application of 5-HT1 and 5-HT2 receptor-selective agonists and antagon... |
| |A-Methylserotonin maleate salt |
| 2-methyl-5-HT |
| HMS3262F07 |