Desmethylcitalopram (hydrochloride)

Modify Date: 2024-01-19 12:16:30

Desmethylcitalopram (hydrochloride) Structure
Desmethylcitalopram (hydrochloride) structure
Common Name Desmethylcitalopram (hydrochloride)
CAS Number 97743-99-2 Molecular Weight 346.82600
Density N/A Boiling Point N/A
Molecular Formula C19H20ClFN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desmethylcitalopram (hydrochloride)


Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].

 Names

Name 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile,hydrochloride
Synonym More Synonyms

 Desmethylcitalopram (hydrochloride) Biological Activity

Description Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].
Related Catalog
References

[1]. von Moltke LL, et aI. Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects. Biol Psychiatry. 1999 Sep 15;46(6):839-49.  

 Chemical & Physical Properties

Molecular Formula C19H20ClFN2O
Molecular Weight 346.82600
Exact Mass 346.12500
PSA 45.05000
LogP 4.66368

 Synonyms

UNII-461OE8B9GL
rac Desmethyl Citalopram Hydrochloride
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