3,4'-Dihydroxy-3',5,7-trimethoxyflavan

Modify Date: 2024-01-09 02:06:44

3,4'-Dihydroxy-3',5,7-trimethoxyflavan Structure
3,4'-Dihydroxy-3',5,7-trimethoxyflavan structure
Common Name 3,4'-Dihydroxy-3',5,7-trimethoxyflavan
CAS Number 97914-19-7 Molecular Weight 332.35
Density 1.3±0.1 g/cm3 Boiling Point 541.1±50.0 °C at 760 mmHg
Molecular Formula C18H20O6 Melting Point N/A
MSDS N/A Flash Point 281.0±30.1 °C

 Use of 3,4'-Dihydroxy-3',5,7-trimethoxyflavan


5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer [1].

 Names

Name 3,4'-Dihydroxy-3',5,7-trimethoxyflavan
Synonym More Synonyms

 3,4'-Dihydroxy-3',5,7-trimethoxyflavan Biological Activity

Description 5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer [1].
Related Catalog
References

[1]. Lee JS, et al. Inhibition of phospholipase Cgamma1 and cancer cell proliferation by lignans and flavans from Machilus thunbergii. Arch Pharm Res. 2004 Oct;27(10):1043-7  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 541.1±50.0 °C at 760 mmHg
Molecular Formula C18H20O6
Molecular Weight 332.35
Flash Point 281.0±30.1 °C
Exact Mass 332.125977
PSA 77.38000
LogP 1.49
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.595

 Safety Information

Hazard Codes Xi
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2H-1-Benzopyran-3-ol, 3,4-dihydro-2-(4-hydroxy-3-methoxyphenyl)-5,7-dimethoxy-
2-(4-Hydroxy-3-methoxyphenyl)-5,7-dimethoxy-3-chromanol