4712-12-3

4712-12-3 structure

Name: 4'-Methylchrysoeriol
Chemical Name: 2-(3,4-dimethoxyphenyl)-5,7-dihydroxychromen-4-one
CAS Number: 4712-12-3
Molecular Formula: C₁₇H₁₄O₆
Molecular Weight: 314.28900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2017-11-12 01:16:20
Modify Date: 2025-08-20 11:32:03
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.

Name	2-(3,4-dimethoxyphenyl)-5,7-dihydroxychromen-4-one
Synonyms	Kaempferol 3,4'-dimethyl ether 5,7-dihydroxy-3',4'-dimethoxyflavone 3',4'-dimethoxy-5,7-dihydroxyflavone 3'4'-dimethoxyluteolin Kampferol-3,4'-dimethyl ether luteolin-3',4'-dimethyl ether

Description	4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Cancer
Target	IC50: 19 nM ( human P450 1B1-dependent EROD)[1].
In Vitro	4'-Methylchrysoeriol (34DM57DHF) is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC50 of 19 nM for human P450 1B1-dependent EROD[1].
References	[1]. Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33.