isodispar B
Modify Date: 2024-01-09 12:19:13
isodispar B structure
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Common Name | isodispar B | ||
|---|---|---|---|---|
| CAS Number | 98192-64-4 | Molecular Weight | 338.35400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H18O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of isodispar BIsodispar B is an anticancer agent that inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells and induces cell apoptosis. Isodispar B is cytotoxic to a wide range of cancer cell lines[1]. |
| Name | isodispar B |
|---|---|
| Synonym | More Synonyms |
| Description | Isodispar B is an anticancer agent that inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells and induces cell apoptosis. Isodispar B is cytotoxic to a wide range of cancer cell lines[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Isodispar B (化合物 1) (0-100 μM; 72 h) 具有广谱的抗癌活性，抑制细胞增殖，IC50 为 3.84-56.73 μM[1]。 Isodispar B (1 μM 和 10 μM; 3 d) 诱导鼻咽癌细胞 (TW01、CNE1、HK1、SUNE1) 凋亡[1]。 Cell Cytotoxicity Assay[1] Cell Line: Nasopharyngeal cancer cells (TW01, CNE1, HK1, and SUNE1) and noncancerous nasopharyngeal cells (NP460) Concentration: 0-100 μM Incubation Time: 72 hours Result: Showed cytotoxicity and inhibited cell viability with IC50s of 3.84 μM (SUNE1), 11.49 μM (TW01), 9.74 μM (CNE1), 5.58 μM (HK1), 56.73 μM (HCC38), 52.69 μM (MDA-MB-231), 52.75 μM (MDA-ME-468), and 54.85 μM (SKBR3), respectively. |
| References |
| Molecular Formula | C20H18O5 |
|---|---|
| Molecular Weight | 338.35400 |
| Exact Mass | 338.11500 |
| PSA | 87.74000 |
| LogP | 4.10000 |
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