IX 207-887

Modify Date: 2024-01-02 18:35:32

IX 207-887 Structure
IX 207-887 structure
Common Name IX 207-887
CAS Number 98320-39-9 Molecular Weight 284.33000
Density N/A Boiling Point N/A
Molecular Formula C16H12O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IX 207-887


IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

 Names

Name Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)
Synonym More Synonyms

 IX 207-887 Biological Activity

Description IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
Related Catalog
Target

Interleukin-1[1]

In Vitro IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].
References

[1]. Schnyder J, et al. Inhibition of interleukin-1 release by IX 207-887. Agents Actions. 1990 Jun;30(3-4):350-62.

 Chemical & Physical Properties

Molecular Formula C16H12O3S
Molecular Weight 284.33000
Exact Mass 284.05100
PSA 74.77000
LogP 3.72230

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

IX 207887
4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, acetic acid deriv.
(Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID
Acetic acid, (10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-
IX 207-887