Nitrocaramiphen hydrochloride

Modify Date: 2024-01-20 12:35:20

Nitrocaramiphen hydrochloride structure	Common Name	Nitrocaramiphen hydrochloride
	CAS Number	98636-73-8	Molecular Weight	370.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₇ClN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nitrocaramiphen hydrochloride

Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (Ki: 5.5 nM). Nitrocaramiphen Hydrochloride inhibits the hyperpolarizing effect of muscarine in the muscle fibers[1][2][3].

Name	Nitrocaramiphen hydrochloride
Synonym	More Synonyms

Description	Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (Ki: 5.5 nM). Nitrocaramiphen Hydrochloride inhibits the hyperpolarizing effect of muscarine in the muscle fibers[1][2][3].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	Ki: 5.5 nM (M1 receptor)[2]
References	[1]. Hussain RI, et al. Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. Br J Pharmacol. 2009 Feb;156(4):575-86. [2]. Hudkins RL, et al. Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarinic M1 receptor-selective agents. Eur J Pharmacol. 1993 Feb 16;231(3):485-8. [3]. Naumenko NV, et al. [Pharmacological parameters of muscarinic cholinoreceptors in skeletal muscles]. Ross Fiziol Zh Im I M Sechenova. 2002 May;88(5):619-26.

Molecular Formula	C₁₈H₂₇ClN₂O₄
Molecular Weight	370.87
Exact Mass	370.16600
PSA	75.36000
LogP	4.61680
Storage condition	-20°C

[Sar9,Met(O2)11]-Substance P

Nitrocaramiphen hydrochloride

Use of Nitrocaramiphen hydrochloride

Names

Nitrocaramiphen hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms