DMT-dA(bz) Phosphoramidite

Modify Date: 2024-01-03 22:02:05

DMT-dA(bz) Phosphoramidite Structure
DMT-dA(bz) Phosphoramidite structure
 Common Name DMT-dA(bz) Phosphoramidite
CAS Number 98796-53-3 Molecular Weight 857.932
Density N/A Boiling Point N/A
Molecular Formula C47H52N7O7P Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of DMT-dA(bz) Phosphoramidite


DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[1].

 Names

Name DMT-dA(bz) Phosphoramidite
Synonym More Synonyms

 DMT-dA(bz) Phosphoramidite Biological Activity

Description DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[1].
Related Catalog
References

[1]. James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.

 Chemical & Physical Properties

Molecular Formula C47H52N7O7P
Molecular Weight 857.932
Exact Mass 857.366577
PSA 168.70000
LogP 9.95
Appearance of Characters white to off-white
Storage condition Store at -20°C
Water Solubility soluble, clear

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2903890090

 Synthetic Route

O-β-cyanoethyl-N,N,N',N'-tetraisopropylphosphoramidite structure

O-β-cyanoethyl-...

CAS#:131420-63-8

N6-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxyadenosine structure

N6-Benzoyl-5'-O...

CAS#:64325-78-6

~85%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: AVECIA BIOTECHNOLOGY INC.; AVECIA LIMITED Patent: WO2004/35599 A1, 2004 ; Location in patent: Page 9-10 ;
2-Cyanoethyltetraisopropylphosphorodiamidite structure

2-Cyanoethyltet...

CAS#:102691-36-1

N6-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxyadenosine structure

N6-Benzoyl-5'-O...

CAS#:64325-78-6

~10%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Dabkowski, Wojciech; Tworowska, Izabela; Michalski, Jan; Cramer, Friedrich Chemical Communications, 1997 , # 9 p. 877 - 878
2-cyanoethyl N,N- diisopropylchlorophosphoramidite structure

2-cyanoethyl N,...

CAS#:124482-92-4

N6-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxyadenosine structure

N6-Benzoyl-5'-O...

CAS#:64325-78-6

~89%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Amigues, Eric J.; Hardacre, Christopher; Keane, Gillian; Migaud, Marie E.; Norman, Sarah E.; Pitner, William R. Green Chemistry, 2009 , vol. 11, # 9 p. 1391 - 1396
N-(9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((bis(diisopropylamino)phosphanyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide structure

N-(9-((2R,4S,5R...

CAS#:133728-84-4

hydracrylonitrile structure

hydracrylonitrile

CAS#:109-78-4

~%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: US6335439 B1, ; Example 14 ;
2-cyanoethyl N,N- diisopropylchlorophosphoramidite structure

2-cyanoethyl N,...

CAS#:124482-92-4

~%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Tetrahedron Letters, , vol. 37, # 3 p. 331 - 334
N6-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxyadenosine structure

N6-Benzoyl-5'-O...

CAS#:64325-78-6

2-cyanoethoxy(N,N-diisopropylamino)3-nitro-1,2,4-triazolylphosphine structure

2-cyanoethoxy(N...

CAS#:174647-46-2

~%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Tetrahedron Letters, , vol. 37, # 3 p. 331 - 334
Diisopropylaminotrimethylsilane structure

Diisopropylamin...

CAS#:17425-88-6

~%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Tetrahedron Letters, , vol. 24, # 52 p. 5843 - 5846
Diisopropylamine structure

Diisopropylamine

CAS#:108-18-9

~%

DMT-dA(bz) Phosphoramidite Structure

DMT-dA(bz) Phos...

CAS#:98796-53-3

Literature: Tetrahedron Letters, , vol. 24, # 52 p. 5843 - 5846

 Customs

HS Code 2903890090
Summary 2903890090. halogenated derivatives of cyclanic, cyclenic or cyclotherpenic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-deoxy-
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
(2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyadenosine
DMT-dA(Bz)-CE-Phosphoramidite
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