Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

Modify Date: 2024-01-12 14:01:32

Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt Structure
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt structure
Common Name Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
CAS Number 98992-65-5 Molecular Weight 655.846
Density 1.2±0.1 g/cm3 Boiling Point 893.7±65.0 °C at 760 mmHg
Molecular Formula C31H53N5O8S Melting Point N/A
MSDS N/A Flash Point 494.3±34.3 °C

 Use of Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt


Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity[1].

 Names

Name mmp-2/mmp-9 substrate ii
Synonym More Synonyms

  Biological Activity

Description Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity[1].
Related Catalog
References

[1]. Dong XW, et al. Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles. Eur J Med Chem. 2019 Feb 15;164:602-614.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 893.7±65.0 °C at 760 mmHg
Molecular Formula C31H53N5O8S
Molecular Weight 655.846
Flash Point 494.3±34.3 °C
Exact Mass 655.361511
PSA 205.38000
LogP 4.10
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.517

 Synonyms

Glycine, N-[(2S)-2-[[2-[[(2S)-2-[[[(2S)-1-acetyl-2-pyrrolidinyl]carbonyl]amino]-4-methyl-1-oxopentyl]amino]acetyl]thio]-4-methyl-1-oxopentyl]-L-leucyl-, ethyl ester
Ethyl N-{(2S)-2-[(1-acetyl-L-prolyl-L-leucylglycyl)sulfanyl]-4-methylpentanoyl}-L-leucylglycinate