Prosaikogenin G

Modify Date: 2024-01-12 12:08:22

Prosaikogenin G structure	Common Name	Prosaikogenin G
	CAS Number	99365-23-8	Molecular Weight	618.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₅₈O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Prosaikogenin G

Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].

Name	Prosaikogenin G

Description	Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC[1].
References	[1]. Nan Xu, et al. A new saikogenin from the roots of Bupleurum bicaule. Chin J Nat Med. 2014 Apr;12(4):305-8. [2]. Pei Yu, et al. In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes. Xenobiotica. 2017 Jan;47(1):11-19.

Molecular Formula	C₃₆H₅₈O₈
Molecular Weight	618.84

Hazard Codes	Xi

Prosaikogenin G

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