Aminoguanidine hemisulfate

Modify Date: 2024-01-12 02:41:55

Aminoguanidine hemisulfate Structure
Aminoguanidine hemisulfate structure
 Common Name Aminoguanidine hemisulfate
CAS Number 996-19-0 Molecular Weight 123.13
Density N/A Boiling Point 261.4ºC at 760mmHg
Molecular Formula CH6N4.1/2H2O4 Melting Point 200 °C
MSDS USA Flash Point 111.9ºC
Purity Quantity Budget Inquiry

 Use of Aminoguanidine hemisulfate


Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research[1].

 Names

Name Aminoguanidine Hemisulfate
Synonym More Synonyms

 Aminoguanidine hemisulfate Biological Activity

Description Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research[1].
Related Catalog
Target

IC50: ROS, NOS[1]

References

[1]. Po-Li Wei, et al. Areca nut extract (ANE) inhibits the progression of hepatocellular carcinoma cells via activation of ROS production and activation of autophagy. Int J Med Sci. 2021 Aug 9;18(15):3452-3462.  

[2]. You-Ting Zhu, et al. Effects of L-arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus. Genes (Basel). 2023 Feb 9;14(2):450.  

 Chemical & Physical Properties

Boiling Point 261.4ºC at 760mmHg
Melting Point 200 °C
Molecular Formula CH6N4.1/2H2O4
Molecular Weight 123.13
Flash Point 111.9ºC
Exact Mass 246.085876
PSA 258.82000
LogP 0.89680

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
HS Code 2925290090

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles4

More Articles
Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

PLoS ONE 10(1) , e0117842, (2015)

Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n...

A simple assay for mammalian spermine oxidase: a polyamine catabolic enzyme implicated in drug response and disease.

Methods Mol. Biol. 720 , 173-81, (2011)

Spermine oxidase (SMO), the most recently characterized polyamine metabolic enzyme, catalyzes the direct back-conversion of spermine to spermidine in an FAD-dependent reaction that also yields the byp...

Effects of nitric oxide on ovulation and ovarian steroidogenesis and prostaglandin production in the rabbit.

Endocrinology 138 , 3630-7, (1997)

Evidence supports the involvement of nitric oxide (NO) in ovarian physiology. The present study was undertaken to investigate the role of the NO/NO synthase (NOS) systems in ovulation, oocyte maturati...

 Synonyms

EINECS 213-628-7
Carbonohydrazonic diamide, sulfate (2:1)
Aminoguanidine hemisulfate
Bis(carbamimidoylhydrazinium) sulfate
MFCD00035665
Carbonohydrazonic diamide sulfate (2:1)
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