Methyl indole-5-carboxylate

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Names

[ CAS No. ]:
1011-65-0

[ Name ]:
Methyl indole-5-carboxylate

[Synonym ]:
Indole-5-carboxylic acid,methyl ester
Methyl 1H-indole-5-carboxylate
1H-Indole-5-carboxylic acid, methyl ester
MFCD00153023
Indole-5-carboxylic Acid Methyl Ester
Methyl indole-5-carboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
331.7±15.0 °C at 760 mmHg

[ Melting Point ]:
126-128 °C(lit.)

[ Molecular Formula ]:
C10H9NO2

[ Molecular Weight ]:
175.184

[ Flash Point ]:
154.4±20.4 °C

[ Exact Mass ]:
175.063324

[ PSA ]:
42.09000

[ LogP ]:
2.58

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.639

[ Storage condition ]:
Refrigerator

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • Indole-5-carboxylic Acid
  • Dimethyl sulfate
  • methyl iodide
  • 1H-Indole-6-carboxylic acid
  • dead
  • ethene
  • methyl 3-bromo-4-nitrobenzoate

DownStream

  • methyl 1-[(3-nitrophenyl)methyl]indole-5-carboxylate
  • Methyl 3-Bromoindole-5-carboxylate
  • Methyl 3-formyl-1H-indole-5-carboxylate
  • 5-carboxyisatin methyl ester
  • Indole-5-Methanol
  • Indole-5-carboxaldehyde
  • Methyl indoline-5-carboxylate
  • methyl 1-methylindole-5-carboxylate
  • Indole-5-carboxylic Acid
  • 5-Indolinecarboxylic acid

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and antimalarial testing of neocryptolepine analogues: addition of ester function in SAR study of 2,11-disubstituted indolo[2,3-b]quinolines.

Eur. J. Med. Chem. 64 , 498-511, (2013)

This report describes the synthesis, and in vitro and in vivo antimalarial evaluations of certain ester-modified neocryptolepine (5-methyl-5H-indolo[2,3-b]quinoline) derivatives. The modifications wer...

Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo.

PLoS ONE 7(8) , e43645, (2012)

Recently, histone deacetylase (HDAC) inhibitors have emerged as a promising class of drugs for treatment of cancers, especially subcutaneous T-cell lymphoma. In this study, we demonstrated that MPT0E0...

Copper-catalyzed cross dehydrogenative coupling reactions of tertiary amines with ketones or indoles.

Org. Lett. 12 , 5214, (2010)

A novel cross dehydrogenative coupling (CDC) reaction of N,N-dimethylanilines with methyl ketones by cooperative copper and aminocatalysis has been developed, which leads to the formation of β-arylami...


More Articles


Related Compounds

  • methyl 1-[(3-nitrophenyl)methyl]indole-5-carboxylate
  • Methyl 6-methoxy-1H-indole-5-carboxylate
  • methyl 3-(cyanomethyl)-1H-indole-5-carboxylate
  • Methyl 3-nitro-1H-indole-5-carboxylate
  • Methyl 6-chloro-1H-indole-5-carboxylate
  • Methyl 7-bromo-1H-indole-5-carboxylate
  • CID 68974124
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  • 5-(Morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one; carbonic acid
  • 2-{[(2-Chlorophenyl)methyl]amino}propane-1,3-diol
  • 5-(Furan-2-yl)-4-methyl-1,2,3,6-tetrahydropyridine hydrochloride
  • Methyl 3-[(methylamino)carbonyl]-5-(5-methylpyridin-2-yl)benzoate
  • 1-(Azetidin-3-yl)-3-methylurea hydrochloride
  • Methyl 3-(5-methylpyridin-2-yl)-5-(1-((trimethylsilyl)methyl)-1H-1,2,3-triazol-5-yl)benzoate
  • 5-fluoro-6-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride