Methyl indole-5-carboxylate
Methyl indole-5-carboxylate structure
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Common Name | Methyl indole-5-carboxylate | ||
|---|---|---|---|---|
| CAS Number | 1011-65-0 | Molecular Weight | 175.184 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 331.7±15.0 °C at 760 mmHg | |
| Molecular Formula | C10H9NO2 | Melting Point | 126-128 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 154.4±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis and antimalarial testing of neocryptolepine analogues: addition of ester function in SAR study of 2,11-disubstituted indolo[2,3-b]quinolines.
Eur. J. Med. Chem. 64 , 498-511, (2013) This report describes the synthesis, and in vitro and in vivo antimalarial evaluations of certain ester-modified neocryptolepine (5-methyl-5H-indolo[2,3-b]quinoline) derivatives. The modifications were carried out by introducing ester groups at the C2 and/or ... |
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Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo.
PLoS ONE 7(8) , e43645, (2012) Recently, histone deacetylase (HDAC) inhibitors have emerged as a promising class of drugs for treatment of cancers, especially subcutaneous T-cell lymphoma. In this study, we demonstrated that MPT0E028, a novel N-hydroxyacrylamide-derived HDAC inhibitor, inh... |
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Copper-catalyzed cross dehydrogenative coupling reactions of tertiary amines with ketones or indoles.
Org. Lett. 12 , 5214, (2010) A novel cross dehydrogenative coupling (CDC) reaction of N,N-dimethylanilines with methyl ketones by cooperative copper and aminocatalysis has been developed, which leads to the formation of β-arylamino ketones in 42-73% yields. Moreover, the copper-catalyzed... |
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A direct ylide transfer to carbonyl derivatives and heteroaromatic compounds.
Angew. Chem. Int. Ed. Engl. 49 , 8979, (2010)
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Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6.
Chem. Biodivers. 2 , 51, (2005) Glycogen synthase kinase-3 (GSK-3) is a potential drug target for a number of human diseases. Some indigoids have been found to be potent inhibitors of GSK-3, and individual compounds with better activity, specificity, and solubility are desired. In this work... |
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Liu, Z.; et al.
Lett. Org. Chem. 7 , 666, (2010)
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Wang, T. C.; et al.
Chin. Chem. Lett. 21 , 1407, (2010)
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Ube, H.; et al.
Tetrahedron Asymmetry 21 , 1203, (2010)
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A facial synthesis and antimicrobial activity of some pyrazole derivatives carrying indole. Sarma KN, et al.
J. Chem. 7(3) , 745-750, (2010)
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