EMD 386088 hydrochloride

Suppliers

Names

[ CAS No. ]:
1171123-46-8

[ Name ]:
EMD 386088 hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C14H16Cl2N2

[ Molecular Weight ]:
283.19600

[ Exact Mass ]:
282.06900

[ PSA ]:
27.82000

[ LogP ]:
4.63720

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Articles

Excess of serotonin affects neocortical pyramidal neuron migration.

Transl. Psychiatry 1 , e47, (2011)

The serotonin transporter (SERT) is a key molecule involved in the homeostasis of extracellular levels of serotonin and is regulated developmentally. Genetic deletion of SERT in rodents increases extr...

5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms.

Br. J. Pharmacol. 167(2) , 436-49, (2012)

5-HT(6) receptors are abundant in the hippocampus, nucleus accumbens and striatum, supporting their role in learning and memory. Selective 5-HT(6) receptor antagonists produce pro-cognitive effects in...

The 5-HT6 receptor agonist EMD 386088 produces antidepressant and anxiolytic effects in rats after intrahippocampal administration.

Psychopharmacology 217(3) , 411-8, (2011)

Preclinical data suggest a possible role for 5-HT6 receptors in depression and anxiety. However, the results of pharmacological studies are equivocal since both blockade and stimulation of 5-HT6 recep...


More Articles

Related Compounds

  • EMD 386088 HYDROCHLORIDE
  • EMD 281014 hydrochloride
  • tert-butyl N-[1-[[2-[[5-[[1-[(6-amino-2-methylpyrimidin-4-yl)methylamino]-3-methyl-1-oxopentan-2-yl]amino]-1-cyclohexyl-3-hydroxy-5-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(2,6-ditritiophenyl)-1-oxopropan-2-yl]carbamate
  • Pramiverin HCl
  • rac Clobenzorex Hydrochloride
  • Ethyl tryptophanate hydrochloride (1:1)
  • 4-Amino-2-(thiophen-3-yl)butan-2-ol
  • 4-Amino-2-methyl-1-phenylbutan-2-ol
  • 3-((3-(Aminomethyl)piperidin-1-yl)methyl)phenol
  • 3-Methylcyclopentane-1-sulfonyl chloride
  • 5-bromo-N-(2,3-dihydroxypropyl)pyridine-2-carboxamide
  • (R,R)-4,4'-Azanediylbis(2,6-di(naphthalen-1-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide)
  • [1-(2-Methylbenzoyl)piperidin-3-yl]methanamine
  • 1-(3-(Aminomethyl)piperidin-1-yl)-2-cyclopentylethan-1-one
  • 5,5-Dimethyl-2-(3-phenylpropyl)-1,3,2-dioxaborinane
  • Ethyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)butanoate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.