4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene

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Names

[ Name ]:
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene

[Synonym ]:
Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
ABBALIDE
Galoxolide
7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene
7-acetyl-1,1,3,4,4,6-hexamethyltetraline
EINECS 214-946-9
5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl-ethanone
7-acetyl-1,1,3,4,4,6-hexamethyl-tetrahydronaphthalene
8-hexamethylcyclopenta[g]-2-benzopyran
MFCD00217003
6-acetyl-1,1,2,4,4,7-hexamethyl-tetralin
Musk50
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
8-Hexahydro-4
PEARLIDE PURE
Pearlide
Galaxolide
Indeno[5,6-c]pyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
6-acetyl-1,1,2,4,4,7-hexamethyl-1,2,3,4-tetrahydronaphthalene
HHCB

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
326.3±11.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₆O

[ Molecular Weight ]:
258.398

[ Flash Point ]:
146.1±15.5 °C

[ Exact Mass ]:
258.198364

[ PSA ]:
9.23000

[ LogP ]:
6.23

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.499

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY0790000

CHEMICAL NAME :: Cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-

CAS REGISTRY NUMBER :: 1222-05-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H26-O

MOLECULAR WEIGHT :: 258.44

WISWESSER LINE NOTATION :: T C566 KOT&TJ D1 D1 E1 E1 F1 F1 M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,793,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0055 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 2279 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0055 No. of Facilities: 3202 (estimated) No. of Industries: 10 No. of Occupations: 11 No. of Employees: 32968 (estimated) No. of Female Employees: 20222 (estimated)

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P391-P501

[ Personal Protective Equipment ]:
Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi: Irritant;N: Dangerous for the environment;

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).

Environ. Pollut. 174 , 214-21, (2013)

This study investigates the metabolism and mode of action of galaxolide (HHCB) in the European sea bass -Dicentrarchus labrax- following a single intraperitoneal injection of 50 mg HHCB/kg body weight...

Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.

Chemosphere 107 , 187-93, (2014)

Continually detected biologically persistent nitromusks; galaxolide (HHCB), tonalide (AHTN) and musk ketone (MK), antimicrobial triclosan (TCS), and antihistamine diphenhydramine (DPH) were examined f...

Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China.

J. Environ. Sci. (China) 23(6) , 983-90, (2011)

Synthetic musks are used as additives in many household products. After absorption into the human body, they accumulate and their concentrations in human milk reflect both the mother and her infant's ...